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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Yokokawa, Miki Good, Eric Chugh, Aman Pelosi, Frank Crawford, Thomas Jongnarangsin, Krit Latchamsetty, Rakesh Oral, Hakan Morady, Fred Bogun, Frank |
| Description | Country affiliation: United States Author Affiliation: Yokokawa M ( Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA.) |
| Abstract | BACKGROUND: Intramural septal idiopathic ventricular arrhythmias have not been described systematically. METHODS AND RESULTS: In a consecutive group of 93 patients with idiopathic ventricular arrhythmias referred for ablation, the site of origin of ventricular arrhythmias was assessed by activation mapping and pace-mapping. In 7 of 93 patients (8%), an intramural focus in the interventricular septum was identified. All ventricular arrhythmias arising intramurally had a left bundle-branch block morphology with inferior axis. The intramural focus was effectively ablated from both sides of the septum in 4 patients and from within the septum in 1 patient. The ablation procedure of an intramural focus near the His bundle failed in 2 of 7 patients. ECG and mapping characteristics of the patients with intramural septal ventricular arrhythmias differentiated intramural arrhythmias from other sites of origin. CONCLUSIONS: Idiopathic septal ventricular arrhythmias can originate from intramural foci. Activation mapping from within a perforator branch within the interventricular septum is helpful in identifying the site of origin of intramural septal arrhythmias. Ablation within the septum or from both sites of the septum may be required to eliminate the targeted arrhythmia. |
| File Format | HTM / HTML |
| ISSN | 19413149 |
| Issue Number | 2 |
| Volume Number | 5 |
| e-ISSN | 19413084 |
| Journal | Circulation: Arrhythmia and Electrophysiology |
| Language | English |
| Publisher | Lippincott Williams & Wilkins |
| Publisher Date | 2012-04-01 |
| Publisher Place | United States |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Cardiology Discipline Vascular Diseases Catheter Ablation Ventricular Fibrillation Etiology Surgery Ventricular Septum Physiopathology Adult Angiography Bundle-branch Block Electrocardiography Female Follow-up Studies Heart Conduction System Humans Male Middle Aged Retrospective Studies Treatment Outcome Journal Article |
| Content Type | Text |
| Resource Type | Article |
| Subject | Physiology (medical) Cardiology and Cardiovascular Medicine |
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