NDLI: Rapid high resolution electroanatomical mapping: evaluation of a new system in a canine atrial linear lesion model.

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Rapid high resolution electroanatomical mapping: evaluation of a new system in a canine atrial linear lesion model.

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Rapid high resolution electroanatomical mapping: evaluation of a new system in a canine atrial linear lesion model.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Nakagawa, Hiroshi Ikeda, Atsushi Sharma, Tushar Lazzara, Ralph Jackman, Warren M.
Description	Country affiliation: United States Author Affiliation: Nakagawa H ( Heart Rhythm Institute and Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA. hiroshi-nakagawa@ouhsc.edu)
Abstract	BACKGROUND: A canine right atrial (RA) linear lesion model was used to produce a complex pattern of RA activation to evaluate a novel mapping system for rapid, high resolution (HR) electroanatomical mapping. METHODS AND RESULTS: The mapping system (Rhythmia Medical, Incorporated) uses an 8F deflectable catheter with a minibasket (1.8 cm diameter), containing 8 splines of 8 electrodes (total 64 electrodes, 2.5 mm spacing). The system automatically acquires electrograms and location information based on electrogram stability and respiration phase. In 10 anesthetized dogs, HR-RA map was obtained by maneuvering the minibasket catheter during sinus rhythm and coronary sinus pacing. A right thoracotomy was performed, and either 1 or 2 (to create a gap) epicardial linear lesions were created on the RA free wall (surgical incision or epicardial radiofrequency lesions). RA maps during RA pacing close to the linear lesions were obtained. A total of 73 maps were created, with 44 to 729 (median 237) beats and 833 to 12 412 (median 3589) electrograms (≤2 to ≤5 mm from surface geometry), resolution 1.8 to 5.3 (median 2.7) mm, and 2.6 to 26.3 (median 7.3) minutes mapping time. Without manual annotation, the system accurately created RA geometry and demonstrated RA activation, identifying the location of lines of block and presence or absence of a gap in all 10 dogs. Endocardial radiofrequency catheter ablation of a gap (guided by activation map) produced complete block across the gap in all 3 dogs tested. CONCLUSIONS: The new HR mapping system accurately and quickly identifies geometry and complex patterns of activation in the canine RA, with little or no manual annotation of activation time.
File Format	HTM / HTML
ISSN	19413149
Issue Number	2
Volume Number	5
e-ISSN	19413084
Journal	Circulation: Arrhythmia and Electrophysiology
Language	English
Publisher	Lippincott Williams & Wilkins
Publisher Date	2012-04-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Cardiology Discipline Vascular Diseases Atrial Function, Right Physiology Body Surface Potential Mapping Methods Electrophysiologic Techniques, Cardiac Heart Atria Anatomy & Histology Animals Instrumentation Cardiac Pacing, Artificial Dogs Electrodes Models, Animal Reproducibility Of Results Sinoatrial Node Evaluation Studies Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Physiology (medical) Cardiology and Cardiovascular Medicine

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