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Detection of schistosomiasis antibodies in urine patients as a promising diagnostic maker.

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Detection of schistosomiasis antibodies in urine patients as a promising diagnostic maker.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Elhag, Salma Medani Abdelkareem, Eshtiyag Abdalla Yousif, Ashraf Siddig Frah, Ehab Ahmed Mohamed, Ahmed Babiker
Spatial Coverage	Sudan
Description	Country affiliation: Sudan Author Affiliation: Elhag SM ( Department of Vector and Biomedical Studies, Tropical Medicine Research Institute, National Centre for Research, Khartoum, Sudan. selmamedani@hotmail.com)
Abstract	OBJECTIVE: To determine secreted antischistosoma antibodies in urine and to discern the epidemiological situation of schistosomiasis in the agricultural field labourers'camps city in the Gezira State-central Sudan. METHODS: Total of 66 urine and 66 serum paired samples were collected from those who confirmed parasitologically positive and negative with schistosomiasis from the two camps. Samples were tested using ELISA technique to measure and compare the immunoglobulin G (IgG) levels in serum and urine samples of schistosomiasis patients. RESULTS: The overall prevalence of S. mansoni and S. haematobium was 53.8% and 15.4%, while the intensity were (2.04 GMEC) and (0.9 GMEC) respectively. The relative percentage of positive IgG individulas in urine was 92.40% where as 96.97% in serum. Statistically no significant difference between the IgG levels in serum and urine samples was observed. CONCLUSIONS: This study shows that the detection of secreted IgG antibodies in urine can substitute serum for diagnosis of schistosomiasis.
File Format	HTM / HTML
ISSN	19957645
e-ISSN	23524146
Journal	Asian Pacific Journal of Tropical Medicine
Issue Number	10
Volume Number	4
Language	English
Publisher	Elsevier
Publisher Date	2011-10-01
Publisher Place	China
Access Restriction	Open
Subject Keyword	Discipline Tropical Medicine Antibodies, Helminth Urine Immunoglobulin G Schistosoma Haematobium Immunology Schistosoma Mansoni Schistosomiasis Haematobia Diagnosis Schistosomiasis Mansoni Adolescent Agricultural Workers' Diseases Epidemiology Animals Blood Biological Markers Child, Preschool Cross-sectional Studies Enzyme-linked Immunosorbent Assay Feasibility Studies Feces Parasitology Parasite Egg Count Sudan Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Medicine

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