NDLI: Diagnostic tools in male infertility-the question of sperm dysfunction.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Barratt, Christopher L. R. Mansell, Steven Beaton, Catherine Tardif, Steve Oxenham, Senga K.
Description	Country affiliation: United kingdom Author Affiliation: Barratt CL ( Reproductive and Developmental Biology, Maternal and Child Health Science Laboratories, Centre for Oncology and Molecular Medicine, Ninewells Hospital, University of Dundee, Dundee, DD1 9SY, Scotland, UK. c.barratt@dundee.ac.uk)
Abstract	Sperm dysfunction is the single most common cause of infertility, yet what is remarkable is that, there is no drug a man can take or add to his spermatozoa in vitro to improve fertility. One reason for the lack of progress in this area is that our understanding of the cellular and molecular workings of the mature spermatazoon is limited. However, over the last few years there has been considerable progress in our knowledge base and in addressing new methods to diagnose sperm dysfunction. We review the current state of the field and provide insights for further development. We conclude that: (i) there is little to be gained from more studies identifying/categorizing various populations of men using a basic semen assessment, where an effort is required in making sure the analysis is performed in an appropriate high quality way; (ii) technological development is likely to bring the reality of sperm function testing closer to implementation into the clinical pathways. In doing this, these assays must be robust, cheap (or more appropriately termed cost effective), easy to use and clinically useful; and (iii) clinical necessity, e.g., the need to identify the highest quality spermatozoon for injection is driving basic research forward. This is an exciting time to be an andrologist and, likely, a fruitful one.
File Format	HTM / HTML
ISSN	1008682X
e-ISSN	17457262
DOI	10.1038/aja.2010.63
Journal	Asian Journal of Andrology
Issue Number	1
Volume Number	13
Language	English
Publisher	Wolters Kluwer - Medknow
Publisher Date	2011-01-01
Publisher Place	China
Access Restriction	Open
Subject Keyword	Discipline Urology Infertility, Male Diagnosis Physiopathology Spermatozoa Physiology Animals Sperm Count Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Urology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Diagnostic tools in male infertility—the question of sperm dysfunction

Semen analysis in 21st century medicine: the need for sperm function testing.

New concepts in Klinefelter syndrome.

Our experience in sperm morphology assessment.

Negative biomarker based male fertility evaluation: Sperm phenotypes associated with molecular-level anomalies.

Redox regulation of mammalian sperm capacitation.

Measurement and significance of sperm morphology.

Lycopene and male infertility.

Mutations of the aurora kinase C gene causing macrozoospermia are the most frequent genetic cause of male infertility in Algerian men.

Diagnostic tools in male infertility-the question of sperm dysfunction.

Similar Documents

Diagnostic tools in male infertility—the question of sperm dysfunction

Semen analysis in 21st century medicine: the need for sperm function testing.

New concepts in Klinefelter syndrome.

Our experience in sperm morphology assessment.

Negative biomarker based male fertility evaluation: Sperm phenotypes associated with molecular-level anomalies.

Redox regulation of mammalian sperm capacitation.

Measurement and significance of sperm morphology.

Lycopene and male infertility.

Mutations of the aurora kinase C gene causing macrozoospermia are the most frequent genetic cause of male infertility in Algerian men.

Diagnostic tools in male infertility-the question of sperm dysfunction.