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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Mateescu, R. G. Thonney, M. L. |
| Spatial Coverage | United States |
| Description | Country affiliation: United States Author Affiliation: Mateescu RG ( Department of Animal Science, Oklahoma State University, Stillwater, OK 74078, USA. raluca@okstate.edu) |
| Abstract | A backcross pedigree using dairy East Friesian rams and non-dairy Dorset ewes was established specifically to map quantitative trait loci (QTL) affecting milk production in sheep. Ninety nine microsatellite markers of an initial set of 120 were successfully genotyped and informative on 188 animals of this backcross pedigree. Test-day milk records on individual ewes were used to estimate several milk yield related traits, including peak milk yield and cumulative milk yield to 50 (MY50), 100 (MY100) and 250 days (MY250). These traits, as well as estimated breeding value of backcross ewes extracted from the genetic evaluation file of the entire flock, were used in interval mapping. Ovine chromosomes 2, 12, 18, 20 and 24 were identified to harbour putative QTL for different measures of milk production. The QTL on Ovis aries chromosomes (OAR) 2 and 20 mapped to locations where similar trait QTL have already been mapped in other studies, whereas QTL on OAR 12, 18 and 24 were unique to our backcross pedigree and have not been reported previously. In addition, all identified QTL regions were syntenic with bovine chromosomal segments revealed to harbour QTL affecting milk production traits, providing supporting evidence for the QTL identified here. |
| File Format | HTM / HTML |
| ISSN | 02689146 |
| Issue Number | 5 |
| Volume Number | 41 |
| e-ISSN | 13652052 |
| Journal | Animal Genetics |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 2010-10-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Genetics Discipline Zoology Lactation Genetics Quantitative Trait Loci Sheep, Domestic Animals Cattle Cheese Economics Crosses, Genetic Female Male Milk Physiology Pedigree Quantitative Trait, Heritable Synteny United States Journal Article Research Support, Non-u.s. Gov't Research Support, U.s. Gov't, Non-p.h.s. |
| Content Type | Text |
| Resource Type | Article |
| Subject | Genetics Medicine Animal Science and Zoology |
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