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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Simkin, S. Hawton, K. Kapur, N. Gunnell, D. |
| Description | Country affiliation: United kingdom Author Affiliation: Simkin S ( Centre for Suicide Research, University of Oxford, Department of Psychiatry, Warneford Hospital, Headington, Oxford, OX3 7JX, UK.) |
| Abstract | BACKGROUND: Paracetamol (acetaminophen) is the most common self-poisoning agent in the UK and a leading cause of fatal hepatotoxicity. Following legislation in 1998 to limit pack sizes, beneficial effects on paracetamol-related mortality and morbidity were reported in England. However, there are still over 100 deaths a year and evidence of breaches of sales guidelines. AIM: To investigate characteristics of people taking larger paracetamol overdoses and compliance with sales guidelines, to inform possible further initiatives to reduce paracetamol fatalities. DESIGN AND METHODS: Interview study of 60 general hospital patients who took overdoses of over 16 paracetamol tablets (8 g). RESULTS: Half of all paracetamol overdoses involved over 16 tablets. Patients were predominantly young (three-quarters aged 16-40 years) and female (58.3%); over half (53.3%) had taken a previous paracetamol overdose. Three-quarters said they wanted to die. Half took the overdose within an hour of first thinking of it, half (53.3%) took tablets already in the home and 58.3% bought tablets specifically for the overdose. Ten people tried to buy more than 32 tablets in one transaction; four succeeded. Most knew that a paracetamol overdose could cause death or permanent damage (88.3%) and harm the liver (80.0%) but 70.0% thought they would lose consciousness. Warnings on packs had little deterrent effect. Media and internet influences were identified. Patients chose paracetamol because it was cheap and easily available. CONCLUSIONS: Further measures to reduce breaches of sales guidelines and the dangers of paracetamol overdose are required. Media and internet site producers should follow guidelines on reporting suicide. |
| File Format | HTM / HTML |
| ISSN | 14602725 |
| e-ISSN | 14602393 |
| Journal | QJM |
| Issue Number | 1 |
| Volume Number | 105 |
| Language | English |
| Publisher | Oxford University Press |
| Publisher Date | 2012-01-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | Open |
| Subject Keyword | Discipline Medicine Acetaminophen Poisoning Analgesics, Non-narcotic Supply & Distribution Adolescent Choice Behavior Drug Labeling Drug Overdose Prevention & Control Psychology Guidelines As Topic Health Knowledge, Attitudes, Practice Motivation Practice Guidelines As Topic Suicide, Attempted Statistics & Numerical Data Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine |
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