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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Kim, Christina K. Yang, Samuel J. Pichamoorthy, Nandini Young, Noah P. Kauvar, Isaac Jennings, Joshua H. Lerner, Talia N. Berndt, Andre Lee, Soo Yeun Ramakrishnan, Charu Davidson, Thomas J. Inoue, Masatoshi Bito, Haruhiko Deisseroth, Karl |
| Description | Country affiliation: United States Author Affiliation: Kim CK ( Neurosciences Program, Stanford University, Stanford, California, USA.); Yang SJ ( Department of Electrical Engineering, Stanford University, Stanford, California, USA.); Pichamoorthy N ( Department of Bioengineering, Stanford University, Stanford, California, USA.); Young NP ( Department of Bioengineering, Stanford University, Stanford, California, USA.); Kauvar I ( Department of Electrical Engineering, Stanford University, Stanford, California, USA.); Jennings JH ( Department of Bioengineering, Stanford University, Stanford, California, USA.); Lerner TN ( Department of Bioengineering, Stanford University, Stanford, California, USA.); Berndt A ( Department of Bioengineering, Stanford University, Stanford, California, USA.); Lee SY ( Department of Bioengineering, Stanford University, Stanford, California, USA.); Ramakrishnan C ( Department of Bioengineering, Stanford University, Stanford, California, USA.); Davidson TJ ( Department of Bioengineering, Stanford University, Stanford, California, USA.); Inoue M ( Department of Neurochemistry, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.); Bito H ( Core Research for Evolutional Science and Technology, Japan Agency for Medical Research and Development, Tokyo, Japan.); Deisseroth K ( Department of Neurochemistry, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.) |
| Abstract | Real-time activity measurements from multiple specific cell populations and projections are likely to be important for understanding the brain as a dynamical system. Here we developed frame-projected independent-fiber photometry (FIP), which we used to record fluorescence activity signals from many brain regions simultaneously in freely behaving mice. We explored the versatility of the FIP microscope by quantifying real-time activity relationships among many brain regions during social behavior, simultaneously recording activity along multiple axonal pathways during sensory experience, performing simultaneous two-color activity recording, and applying optical perturbation tuned to elicit dynamics that match naturally occurring patterns observed during behavior. |
| File Format | HTM / HTML |
| ISSN | 15487091 |
| Issue Number | 4 |
| Volume Number | 13 |
| e-ISSN | 15487105 |
| Journal | Nature Methods |
| Language | English |
| Publisher | Nature Publishing Group |
| Publisher Date | 2016-04-01 |
| Publisher Place | United States |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Clinical Laboratory Techniques Brain Mapping Methods Brain Physiology Calcium Signaling Neural Pathways Photometry Social Behavior Animals Cytology Mice Journal Article Research Support, N.i.h., Extramural Research Support, Non-u.s. Gov't Research Support, U.s. Gov't, Non-p.h.s. |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cell Biology Biochemistry Molecular Biology Biotechnology |
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