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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Little, Peter J. Rostam, Muhamad Ashraf Piva, Terrence J. Getachew, Robel Kamato, Danielle Guidone, Daniel Ballinger, Mandy L. Zheng, Wenhua Osman, Narin |
| Description | Country affiliation: Australia Author Affiliation: Little PJ ( Discipline of Pharmacy, School of Medical Sciences, Diabetes Complications Group, Health Innovations Research Institute, Melbourne, VIC, Australia. peter.little@rmit.edu.au) |
| Abstract | Objectives Suramin is a polysulfonated naphthylurea with antiparasitic and potential antineoplastic activity. Suramin's pharmacological actions, which have not yet been fully elucidated, include antagonism of the action of platelet-derived growth factor (PDGF) at its receptor. We investigated the effects of suramin on PDGF-stimulated proteoglycan synthesis. |
| File Format | HTM / HTML |
| ISSN | 00223573 |
| Issue Number | 7 |
| Volume Number | 65 |
| e-ISSN | 20427158 |
| Journal | Journal of Pharmacy and Pharmacology |
| Language | English |
| Publisher | Wiley |
| Publisher Date | 2013-07-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Pharmacology Antineoplastic Agents Pharmacology Platelet-derived Growth Factor Metabolism Suramin Cell Proliferation Drug Effects Electrophoresis, Polyacrylamide Gel Glycosaminoglycans Humans Muscle, Smooth, Vascular Cytology Myocytes, Smooth Muscle Phosphorylation Administration & Dosage Proteoglycans Biosynthesis Receptor, Platelet-derived Growth Factor Beta Receptors, Platelet-derived Growth Factor Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Pharmacology Pharmaceutical Science |
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