NDLI: Rocuronium is associated with an increased risk of reintubation in patients with soft tissue infections.

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Rocuronium is associated with an increased risk of reintubation in patients with soft tissue infections.

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Rocuronium is associated with an increased risk of reintubation in patients with soft tissue infections.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Greco, Karla M. Conti, Bianca M. Bucci, Cynthia J. Galvagno, Samuel M.
Description	Author Affiliation: Greco KM ( Division of Trauma Anesthesiology, Department of Anesthesiology, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD 21201. Electronic address: kgreco@anes.umm.edu.); Conti BM ( Division of Trauma Anesthesiology, Department of Anesthesiology, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD 21201. Electronic address: bconti@anes.umm.edu.); Bucci CJ ( Division of Trauma Anesthesiology, Department of Anesthesiology, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD 21201. Electronic address: cbucci@anes.umm.edu.); Galvagno SM ( Division of Trauma Anesthesiology, Department of Anesthesiology, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD 21201)
Abstract	STUDY OBJECTIVE: To determine risk factors associated with reintubations in adult patients with soft tissue infections. DESIGN: A retrospective case-control design. SETTING: Operating room and postoperative recovery area. PATIENTS: There were 39 patients who presented for surgical intervention of their soft tissue infection and 222 controls having general surgery who were matched for age, sex, and body mass index. All patients were older than the age of 18 years and mostly American Society of Anesthesiologists physical status of III to IV and presented to our level 1 trauma center. INTERVENTIONS: Reintubation within 2 hours after planned extubation. MEASUREMENTS: The following data were collected: reintubation rates, train of four ratio, reversal agents, age, sex, creatinine, smoking history, transfusion requirements, Sequential Organ Failure Assessment score, hemoglobin, and lactate. MAIN RESULTS: The use of rocuronium was independently associated with increased odds of reintubation. Patients with a higher train of four ratio were more likely to be reintubated and less likely to be reversed as compared to those with a lower train of four ratio. CONCLUSIONS: Soft tissue patients who have received rocuronium are at increased risk for reintubation, particularly those with renal failure. In addition, this article supports the use of neuromuscular blockade reversals, even in patients with a strong train of four ratio.
File Format	HTM / HTML
ISSN	09528180
Journal	Journal of Clinical Anesthesia
Volume Number	34
e-ISSN	18734529
Language	English
Publisher	Elsevier
Publisher Date	2016-11-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Anesthesiology
Content Type	Text
Resource Type	Article
Subject	Anesthesiology and Pain Medicine

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