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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Wiedenfeld, H. |
| Spatial Coverage | Ethiopia |
| Description | Country affiliation: Germany Author Affiliation: Wiedenfeld H ( Pharmaceutical Institute, University of Bonn, Bonn, Germany. wiedenfeld@uni-bonn.de) |
| Abstract | Pyrrolizidine alkaloids (PA) are toxic for human and livestock. They undergo a metabolic toxication process in the liver which is the first target organ for PA poisoning. Worldwide many episodes of human PA intoxications are well reported. In many cases the reason for these intoxications has been PA contamination in food. The main tools for analysing food and fodder on PA content are based on GC and HPLC separation, followed by MS(-MS) detection. Actual incidents with toxic PA are the 'Jacobaea vulgaris (syn. Senecio jacobaea) problem' in Europe and the 'Ageratum conyzoides problem' in Ethiopia. |
| File Format | HTM / HTML |
| ISSN | 19440049 |
| Issue Number | 3 |
| Volume Number | 28 |
| e-ISSN | 19440057 |
| Journal | Food Additives & Contaminants: Part A |
| Language | English |
| Publisher | Taylor & Francis |
| Publisher Date | 2011-03-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Toxicology Discipline Nutritional Sciences Plants Chemistry Pyrrolizidine Alkaloids Poisoning Animal Feed Analysis Animals Biotransformation Cytochrome P-450 Enzyme System Metabolism Ethiopia Food Analysis Methods Food Contamination Humans Inactivation, Metabolic Liver Enzymology Liver Failure Chemically Induced Livestock Senecio Journal Article |
| Content Type | Text |
| Resource Type | Article |
| Subject | Chemistry Health, Toxicology and Mutagenesis Public Health, Environmental and Occupational Health Toxicology Food Science |
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