NDLI: Regulation of luteal function and corpus luteum regression in cows: hormonal control, immune mechanisms and intercellular communication.

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Regulation of luteal function and corpus luteum regression in cows: hormonal control, immune mechanisms and intercellular communication.

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Production of transgenic farm animals by viral vector-mediated gene transfer.

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Regulation of luteal function and corpus luteum regression in cows: hormonal control, immune mechanisms and intercellular communication.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Skarzynski, D. J. Ferreira-Dias, G. Okuda, K.
Description	Country affiliation: Poland Author Affiliation: Skarzynski DJ ( Department of Reproductive Immunology, Institute of Animal Reproduction and Food Research of PAS, Olsztyn, Poland. skadar@pan.olsztyn.pl)
Abstract	The main function of the corpus luteum (CL) is production of progesterone (P4). Adequate luteal function to secrete P4 is crucial for determining the physiological duration of the oestrous cycle and for achieving a successful pregnancy. The bovine CL grows very fast and regresses within a few days at luteolysis. Mechanisms controlling development and secretory function of the bovine CL may involve many factors that are produced both within and outside the CL. Some of these regulators seem to be prostaglandins (PGs), oxytocin, growth and adrenergic factors. Moreover, there is evidence that P4 acts within the CL as an autocrine or paracrine regulator. Each of these factors may act on the CL independently or may modify the actions of others. Although uterine PGF(2 alpha) is known to be a principal luteolytic factor, its direct action on the CL is mediated by local factors: cytokines, endothelin-1, nitric oxide. The changes in ovarian blood flow have also been suggested to have some role in regulation of CL development, maintenance and regression.
File Format	HTM / HTML
ISSN	09366768
Issue Number	Suppl 2
Volume Number	43
e-ISSN	14390531
Journal	Reproduction in Domestic Animals
Language	English
Publisher	Wiley
Publisher Date	2008-07-01
Publisher Place	Germany
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Reproductive Medicine Discipline Veterinary Medicine Discipline Zoology Cattle Physiology Corpus Luteum Cytokines Luteolysis Ovulation Animals Blood Supply Dinoprost Female Immunity Progesterone Somatomedins Journal Article Research Support, Non-u.s. Gov't Review
Content Type	Text
Resource Type	Article
Subject	Animal Science and Zoology Endocrinology Biotechnology

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