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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Ueoka, Yoshinori Tomotake, Masahito Tanaka, Tsunehiko Kaneda, Yasuhiro Taniguchi, Kyoko Nakataki, Masahito Numata, Shusuke Tayoshi, Shinya Yamauchi, Ken Sumitani, Satsuki Ohmori, Takashi Ueno, Shu-ichi Ohmori, Tetsuro |
| Description | Country affiliation: Japan Author Affiliation: Ueoka Y ( Department of Psychiatry, Institute of Health Bioscience, The University of Tokushima Graduate School, Japan. y-aiueo@ktd.biglobe.ne.jp) |
| Abstract | The main purpose of the present study was to examine the relationship between quality of life (QOL) and cognitive dysfunction in schizophrenia. Subjects were 61 stabilized outpatients. Quality of life and cognitive function were assessed using the Quality of Life Scale (QLS) and the Brief Assessment of Cognition in Schizophrenia (BACS), respectively. Clinical symptoms were evaluated with the Positive and Negative Syndrome Scale (PANSS) and the Calgary Depression Scale for Schizophrenia (CDSS). The BACS composite score and the BACS Verbal memory score were positively correlated with the QLS total score and two subscales. The BACS Attention and speed of information processing score had positive correlation with the QLS total and all the subscales scores. The PANSS Positive and Negative syndrome scores also had significant correlations with the QLS total score and all of the subscales. In addition, the CDSS score was negatively correlated with the QLS total score and some of the subscales. Stepwise regression analysis showed that the BACS Attention and speed of information processing score was an independent predictor of the QLS total score but it was less associated with the QLS than the PANSS Negative syndrome score and the CDSS score. The results suggest that negative and depressive symptoms are important factors on patients' QOL and also support the view that cognitive performance provides a determinant of QOL in patients with schizophrenia. |
| File Format | HTM / HTML |
| ISSN | 02785846 |
| Issue Number | 1 |
| Volume Number | 35 |
| e-ISSN | 18784216 |
| Journal | Progress in Neuro-Psychopharmacology and Biological Psychiatry |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2011-01-15 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Psychiatry Cognition Disorders Etiology Psychology Quality Of Life Schizophrenia Complications Adult Female Humans Male Middle Aged Neuropsychological Tests Predictive Value Of Tests Psychiatric Status Rating Scales Retrospective Studies Questionnaires Young Adult Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Biological Psychiatry Pharmacology |
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