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Year: 2009 Volume: 51 Issue: 1

Year: 2008 Volume: 50

Year: 2001 Volume: 43

Epidemiology of neonatal sepsis in South Korea.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Shin, Youn-Jeong Ki, Moran Foxman, Betsy
Spatial Coverage	Korea
Description	Author Affiliation: Shin YJ ( Department of Pediatrics, Eulji University Hospital, Eulji University, Daejeon, Korea.)
Abstract	BACKGROUND: Neonatal sepsis is a severe clinical syndrome characterized by systemic signs of infection, shock and system organ failure; diagnosis is confirmed on positive culture from a normally sterile site(s). There are few reports comparing incidence, mortality, and risk factors between clinically diagnosed sepsis and that confirmed by culture. METHODS: All infants diagnosed with early- (within first 72 h after birth) or late-onset (72 h-4 weeks after birth) neonatal sepsis between 1997 and 1999 from four neonatal centers in South Korea, were investigated. RESULTS: The estimated incidence rate of neonatal sepsis during the 3 years was 30.5 per 1000 live births for clinical sepsis and 6.1 per 1000 live births for sepsis with positive culture, with case-fatality rates of 4.7% and 2.2%, respectively. When only early-onset sepsis was considered, the incidence and fatality rates were 25.1 per 1000 live births and 6.1% for clinical sepsis, and 4.3 per 1000 live births and 2.5% for culture-confirmed sepsis, respectively. For the 179 patients (185 causative organisms) of proven sepsis, Staphylococcus spp. including S. aureus were the most frequent isolates. In early-onset clinical sepsis, having very low birthweight (
File Format	HTM / HTML
ISSN	13288067
e-ISSN	1442200X
DOI	10.1111/j.1442-200X.2008.02685.x
Journal	Pediatrics International
Issue Number	2
Volume Number	51
Language	English
Publisher	Wiley
Publisher Date	2009-04-01
Publisher Place	Australia
Access Restriction	Open
Subject Keyword	Discipline Pediatrics Sepsis Epidemiology Age Of Onset Gestational Age Infant, Newborn Korea Meningitis Pneumonia Retrospective Studies Risk Factors Diagnosis Microbiology Urinary Tract Infections Multicenter Study Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Pediatrics, Perinatology and Child Health

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