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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Malinis, Maricar Myers, John Bordon, Jose Peyrani, Paula Kapoor, Rama Nakamatzu, Raul Lopardo, Gustavo Torres, Antoni Feldman, Charles Allen, M. Arnold, F. Ramirez, Julio |
| Description | Country affiliation: United States Author Affiliation: Malinis M ( Division of Infectious Disease, University of Louisville School of Medicine, Louisville, KY, USA.) |
| Abstract | BACKGROUND: There are limited and conflicting data on clinical outcomes of community-acquired pneumonia (CAP) among HIV-infected patients. METHODS: Secondary analyses of clinical outcomes of CAP were performed for 118 patients with HIV infection and 2790 patients without HIV infection enrolled in the Community-Acquired Pneumonia Organization (CAPO) international study. After adjustment for significant confounders, the effect of HIV infection on length of stay (LOS) and time to clinical stability (TCS) were examined by survival analyses and overall mortality and CAP-related mortality by logistic regression methods. RESULTS: After adjusting for significant confounders, hospitalized HIV-infected patients with CAP did not have longer times to reach clinical stability (HR 1.126; 95% CI 0.917-1.391; p=0.251) or longer stays in the hospital (HR 1.191, 95% CI 0.979-1.449; p=0.080). In addition, HIV infection did not significantly influence overall mortality rates (OR 1.205, 95% CI 0.686-2.116; p=0.517) or CAP-related mortality rates (OR 1.338; 95% CI 0.623-3.725; p=0.355). CONCLUSION: The presence of HIV infection did not influence the clinical outcomes of CAP among patients assessed at CAPO centers. It is not intended that our results be extrapolated to populations receiving limited healthcare for advanced HIV disease, malnourishment and parasitic diseases. |
| File Format | HTM / HTML |
| ISSN | 12019712 |
| e-ISSN | 18783511 |
| Journal | International Journal of Infectious Diseases |
| Issue Number | 1 |
| Volume Number | 14 |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2010-01-01 |
| Publisher Place | Canada |
| Access Restriction | Open |
| Subject Keyword | Discipline Communicable Diseases Community-acquired Infections Therapy Hiv Infections Complications Pneumonia, Bacterial Mortality Global Health Length Of Stay Outcome Assessment (health Care) Retrospective Studies Severity Of Illness Index Survival Analysis |
| Content Type | Text |
| Resource Type | Article |
| Subject | Infectious Diseases Microbiology (medical) |
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