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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Capodanno, Davide Tamburino, Corrado Dangas, George |
| Description | Country affiliation: Italy Author Affiliation: Capodanno D ( University of Catania, Ferrarotto Hospital, Via Citelli, 6, 95124 Catania, Italy.) |
| Abstract | INTRODUCTION: Adjunctive pharmacotherapy is of key importance in determining the outcomes of percutaneous coronary intervention (PCI). In parallel, there has been an increasing body of evidence indicating that the aggressive management of coronary risk factors and changes in lifestyle behavior yield additional positive results in morbidity and mortality reductions. A stream of new data from randomized clinical trials has recently prompted the release of a focused update of the PCI guidelines, endorsing new recommendations on the use of antiplatelet drugs and parenteral anticoagulants. AREAS COVERED: The aim of this manuscript is to provide an up-to-date overview of the current evidence on the use of adjunctive pharmacological therapy in patients undergoing revascularization, with focus on results of recent trials and future directions. EXPERT OPINION: Given the availability of several pharmacological agents with different mechanisms of action, understanding whether a drug should or should not be prescribed, as well as individualizing the pharmacological formula to the patient's need and risk category, is pivotal to balance the safety and efficacy of adjunctive therapies for PCI. Studies on new antiplatelet agents and selective inhibitors of specific coagulation factors are likely to characterize the next years of research on interventional pharmacology. |
| File Format | HTM / HTML |
| ISSN | 14656566 |
| Issue Number | 7 |
| Volume Number | 12 |
| e-ISSN | 17447666 |
| Journal | Expert Opinion on Pharmacotherapy |
| Language | English |
| Publisher | Taylor & Francis |
| Publisher Date | 2011-05-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Pharmacology Angioplasty, Balloon, Coronary Anticoagulants Therapeutic Use Fibrinolytic Agents Platelet Aggregation Inhibitors Risk Reduction Behavior Adverse Effects Combined Modality Therapy Female Humans Male Randomized Controlled Trials As Topic Journal Article Review |
| Content Type | Text |
| Resource Type | Article |
| Subject | Pharmacology Pharmacology (medical) |
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