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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Neffati, A. Bouhlel, I. Ben Sghaier, M. Boubaker, J. Limem, I. Kilani, S. Skandrani, I. Bhouri, W. Le Dauphin, J. Barillier, D. Mosrati, R. Chekir-Ghedira, L. Ghedira, K. |
| Description | Country affiliation: Tunisia Author Affiliation: Neffati A ( Unité de Pharmacognosie/Biologie Moléculaire (99/UR/07-03), Faculté de Pharmacie de Monastir, Rue Avicenne, 5000 Monastir, Tunisia.) |
| Abstract | The SOS-chromotest in Escherichia coli is a widely used bacterial genotoxicity assay to test potential carcinogens. The aim of this work is to evaluate the genotoxic and antigenotoxic activities of essential oils obtained from aerial parts of Pituranthos chloranthus. The tested essential oils were not genotoxic towards both E. coli PQ37 and PQ35 strains. These essential oils reduced significantly Nifuroxazide and H(2)O(2)-induced genotoxicity. Essential oils showed a protective effect against damages induced by radicals, obtained from the photolysis of H(2)O(2), on DNA plasmid through free radical scavenging mechanisms. The scavenging capacity of these essential oils was also estimated by evaluating the inhibition of ABTS(+.) radical. |
| File Format | HTM / HTML |
| ISSN | 13826689 |
| Issue Number | 2 |
| Journal | Environmental Toxicology and Pharmacology |
| Volume Number | 27 |
| e-ISSN | 18727077 |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2009-03-01 |
| Publisher Place | Netherlands |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Environmental Health Discipline Pharmacology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Health, Toxicology and Mutagenesis Medicine Toxicology Pharmacology |
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