NDLI: Evidence for a Specific Integrative Mechanism for Episodic Memory Mediated by AMPA/kainate Receptors in a Circuit Involving Medial Prefrontal Cortex and Hippocampal CA3 Region.

Please wait, while we are loading the content...

Evidence for a Specific Integrative Mechanism for Episodic Memory Mediated by AMPA/kainate Receptors in a Circuit Involving Medial Prefrontal Cortex and Hippocampal CA3 Region.

Prenatal Alcohol Exposure is Associated with Regionally Thinner Cortex During the Preadolescent Period.

Corticostriate Projections from Areas of the 'Lateral Grasping Network': Evidence for Multiple Hand-Related Input Channels.

Cortical Effects on Ipsilateral Hindlimb Muscles Revealed with Stimulus-Triggered Averaging of EMG Activity.

Cdk5 is a New Rapid Synaptic Homeostasis Regulator Capable of Initiating the Early Alzheimer-Like Pathology.

Addressing a Paradox: Dual Strategies for Creative Performance in Introspective and Extrospective Networks.

Dissociations in Cortical Morphometry in Youth with Down Syndrome: Evidence for Reduced Surface Area but Increased Thickness.

There's Waldo! A Normalization Model of Visual Search Predicts Single-Trial Human Fixations in an Object Search Task.

Brain Network Reconfiguration and Perceptual Decoupling During an Absorptive State of Consciousness.

Development of Tool Representations in the Dorsal and Ventral Visual Object Processing Pathways.

Dissociation of Neural Networks for Predisposition and for Training-Related Plasticity in Auditory-Motor Learning.

Remapping, Spatial Stability, and Temporal Continuity: From the Pre-Saccadic to Postsaccadic Representation of Visual Space in LIP.

Expecting to See a Letter: Alpha Oscillations as Carriers of Top-Down Sensory Predictions.

Distinct but Overlapping Patterns of Response to Words and Faces in the Fusiform Gyrus.

Neuroanatomical Evidence in Support of the Bilingual Advantage Theory.

Proper Level of Cytosolic Disabled-1, Which Is Regulated by Dual Nuclear Translocation Pathways, Is Important for Cortical Neuronal Migration.

Separate Brain Circuits Support Integrative and Semantic Priming in the Human Language System.

Early Cerebellar Network Shifting in Spinocerebellar Ataxia Type 6.

High-Resolution Functional Connectivity Density: Hub Locations, Sensitivity, Specificity, Reproducibility, and Reliability.

Subregional Mesiotemporal Network Topology Is Altered in Temporal Lobe Epilepsy.

Network-Level Structure-Function Relationships in Human Neocortex.

Role of the Perigenual Anterior Cingulate and Orbitofrontal Cortex in Contingency Learning in the Marmoset.

Relationship Between Cortical Gyrification, White Matter Connectivity, and Autism Spectrum Disorder.

Neural Representations of Natural and Scrambled Movies Progressively Change from Rat Striate to Temporal Cortex.

Celsr3 and Fzd3 Organize a Pioneer Neuron Scaffold to Steer Growing Thalamocortical Axons.

Year: 2016 Volume: 26 Issue: 6

Year: 2016 Volume: 26 Issue: 5

Year: 2016 Volume: 26 Issue: 4

Year: 2016 Volume: 26 Issue: 3

Year: 2016 Volume: 26 Issue: 2

Year: 2016 Volume: 26 Issue: 1

Year: 2016

Year: 2015 Volume: 25

Year: 2014 Volume: 24

Year: 2013 Volume: 23

Year: 2012 Volume: 22

Year: 2011 Volume: 21

Year: 2010 Volume: 20

Year: 2009 Volume: 19

Year: 2008 Volume: 18

Year: 2007 Volume: 17

Evidence for a Specific Integrative Mechanism for Episodic Memory Mediated by AMPA/kainate Receptors in a Circuit Involving Medial Prefrontal Cortex and Hippocampal CA3 Region.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	de Souza Silva, Maria A. Huston, Joseph P. Wang, An-Li Petri, David Chao, Owen Yuan-Hsin
Description	Country affiliation: Germany Author Affiliation: de Souza Silva MA ( Center for Behavioral Neuroscience, University of Düsseldorf, Düsseldorf 40225, Germany.); Huston JP ( Center for Behavioral Neuroscience, University of Düsseldorf, Düsseldorf 40225, Germany.); Wang AL ( Center for Behavioral Neuroscience, University of Düsseldorf, Düsseldorf 40225, Germany.); Petri D ( Center for Behavioral Neuroscience, University of Düsseldorf, Düsseldorf 40225, Germany.); Chao OY ( Center for Behavioral Neuroscience, University of Düsseldorf, Düsseldorf 40225, Germany.)
Abstract	We asked whether episodic-like memory requires neural mechanisms independent of those that mediate its component memories for 'what,' 'when,' and 'where,' and if neuronal connectivity between the medial prefrontal cortex (mPFC) and the hippocampus (HPC) CA3 subregion is essential for episodic-like memory. Unilateral lesion of the mPFC was combined with unilateral lesion of the CA3 in the ipsi- or contralateral hemispheres in rats. Episodic-like memory was tested using a task, which assesses the integration of memories for 'what, where, and when' concomitantly. Tests for novel object recognition (what), object place (where), and temporal order memory (when) were also applied. Bilateral disconnection of the mPFC-CA3 circuit by N-methyl-d-aspartate (NMDA) lesions disrupted episodic-like memory, but left the component memories for object, place, and temporal order, per se, intact. Furthermore, unilateral NMDA lesion of the CA3 plus injection of (6-cyano-7-nitroquinoxaline-2,3-dione) (CNQX) (AMPA/kainate receptor antagonist), but not AP-5 (NMDA receptor antagonist), into the contralateral mPFC also disrupted episodic-like memory, indicating the mPFC AMPA/kainate receptors as critical for this circuit. These results argue for a selective neural system that specifically subserves episodic memory, as it is not critically involved in the control of its component memories for object, place, and time.
File Format	HTM / HTML
ISSN	10473211
e-ISSN	14602199
Journal	Cerebral Cortex
Issue Number	7
Volume Number	26
Language	English
Publisher	Oxford University Press
Publisher Date	2016-07-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Discipline Neuroscience Discipline Neurology
Content Type	Text
Resource Type	Article
Subject	Cognitive Neuroscience Cellular and Molecular Neuroscience

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Lateralized Contributions of Medial Prefrontal Cortex Network to Episodic Memory Deficits in Subjects With Amnestic Mild Cognitive Impairment

Clmp Regulates AMPA and Kainate Receptor Responses in the Neonatal Hippocampal CA3 and Kainate Seizure Susceptibility in Mice

A Prefrontal-Hippocampal Comparator for Goal-Directed Behavior: The Intentional Self and Episodic Memory

NMDA and AMPA/kainate glutamatergic receptors in the prelimbic medial prefrontal cortex modulate the elaborated defensive behavior and innate fear-induced antinociception elicited by GABAA receptor blockade in the medial hypothalamus.

Medial Prefrontal Activity Predicts Memory for Self

Ontogeny of Kainate-Induced Gamma Oscillations in the Rat CA3 Hippocampus in vitro

Dopamine Modulation of Hippocampal–Prefrontal Cortical Interaction Drives Memory-Guided Behavior

Putting objects in context: A prefrontal–hippocampal–perirhinal cortex network

Lateral and medial prefrontal contributions to emotion generation by semantic elaboration during episodic encoding

Evidence for a Specific Integrative Mechanism for Episodic Memory Mediated by AMPA/kainate Receptors in a Circuit Involving Medial Prefrontal Cortex and Hippocampal CA3 Region.

Similar Documents

Lateralized Contributions of Medial Prefrontal Cortex Network to Episodic Memory Deficits in Subjects With Amnestic Mild Cognitive Impairment

Clmp Regulates AMPA and Kainate Receptor Responses in the Neonatal Hippocampal CA3 and Kainate Seizure Susceptibility in Mice

A Prefrontal-Hippocampal Comparator for Goal-Directed Behavior: The Intentional Self and Episodic Memory

NMDA and AMPA/kainate glutamatergic receptors in the prelimbic medial prefrontal cortex modulate the elaborated defensive behavior and innate fear-induced antinociception elicited by GABAA receptor blockade in the medial hypothalamus.

Medial Prefrontal Activity Predicts Memory for Self

Ontogeny of Kainate-Induced Gamma Oscillations in the Rat CA3 Hippocampus in vitro

Dopamine Modulation of Hippocampal–Prefrontal Cortical Interaction Drives Memory-Guided Behavior

Putting objects in context: A prefrontal–hippocampal–perirhinal cortex network

Lateral and medial prefrontal contributions to emotion generation by semantic elaboration during episodic encoding

Evidence for a Specific Integrative Mechanism for Episodic Memory Mediated by AMPA/kainate Receptors in a Circuit Involving Medial Prefrontal Cortex and Hippocampal CA3 Region.