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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | de Macedo, André Casimiro Santana, Maria Helena Andrade |
| Description | Country affiliation: Brazil Author Affiliation: de Macedo AC ( Laboratory of Development of Biotechnological Processes, School of Chemical Engineering, University of Campinas-UNICAMP, Campinas, SP 13083-852, Brazil.) |
| Abstract | The cashew fruit (Anacardium occidentale L.) has been used as a promising agricultural resource for the production of low-molecular weight (M(W)) hyaluronic acid (HA) (10(4)-10(5) Da). The cashew juice is a rich source of vitamin C containing, 1.2-2.0 g L(-1). This work explores the effects of the initial concentration of the ascorbate on the solid fermentation of the juice-moisturized bagasse from the cashew apple fruit. The results show that the M(W) reduction of HA is proportional to the initial ascorbate concentration. The presence of ascorbate did not influence the Streptococcus zooepidemicus metabolism. However, the HA productivity was increased from 0.18 to 0.28 mg g(-1) h(-1) when the ascorbate concentration ranged from 1.7 to 10 mg mL(-1). These findings contribute to the controlled production of HA in a low M(W) range, which is important in cell signalization, angiogenesis and nanoparticles production. |
| File Format | HTM / HTML |
| ISSN | 09593993 |
| Issue Number | 5 |
| Volume Number | 28 |
| e-ISSN | 15730972 |
| Journal | World Journal of Microbiology and Biotechnology |
| Language | English |
| Publisher | Springer |
| Publisher Date | 2012-05-01 |
| Publisher Place | Germany |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Research Support, Non-u.s. Gov't Discipline Microbiology Hyaluronic Acid Molecular Weight Cellulose Metabolism Fermentation Journal Article Discipline Biotechnology Hydrolysis Growth & Development Ascorbic Acid Chemistry Oxidation-reduction Streptococcus Equi Anacardium |
| Content Type | Text |
| Resource Type | Article |
| Subject | Physiology Medicine Applied Microbiology and Biotechnology Biotechnology |
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