NDLI: Correlations between severity of clinical signs and histopathological changes in 60 dogs with spinal cord injury associated with acute thoracolumbar intervertebral disc disease.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Henke, D. Vandevelde, M. Doherr, M. G. Stöckli, M. Forterre, F.
Spatial Coverage	Switzerland
Description	Author Affiliation: Henke D ( Department of Clinical Veterinary Medicine, Division of Clinical Neurology, Vetsuisse Faculty, University of Bern, Bern 3001, Switzerland. Electronic address: diana.henke@vetsuisse.unibe.ch.)
Abstract	The outcome of spinal surgery in dogs with absent voluntary motor function and nociception following intervertebral disc (IVD) herniation is highly variable, which likely attests to differences in the severity of spinal cord damage. This retrospective study evaluated the extent to which neurological signs correlated with histologically detected spinal cord damage in 60 dogs that were euthanased because of thoracolumbar IVD herniation. Clinical neurological grades correlated significantly with the extent of white matter damage (P<0.001). However, loss of nociception also occurred in 6/31 (19%) dogs with relatively mild histological changes. The duration of clinical signs, Schiff-Sherrington posture, loss of reflexes and pain on spinal palpation were not significantly associated with the severity of spinal cord damage. Although clinical-pathological correlation was generally good, some clinical signs frequently thought to indicate severe cord injury did not always correlate with the degree of cord damage, suggesting functional rather than structural impairment in some cases.
File Format	HTM / HTML
ISSN	10900233
Issue Number	1
Volume Number	198
e-ISSN	15322971
Journal	The Veterinary Journal
Language	English
Publisher	Elsevier
Publisher Date	2013-10-01
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Nociception Complications Discipline Veterinary Medicine Male Switzerland Journal Article Posture Intervertebral Disc Displacement Pathology Spinal Cord Injuries Animals Thoracic Vertebrae Reflex, Abnormal Etiology Dog Diseases Dogs Intervertebral Disc Degeneration Female Retrospective Studies Lumbar Vertebrae Veterinary Injuries
Content Type	Text
Resource Type	Article
Subject	Veterinary Animal Science and Zoology

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