NDLI: Diagnosis and treatment in neuro-oncology: an oncological perspective.

Please wait, while we are loading the content...

Year: 2017 Volume: 90

Year: 2016 Volume: 89

Year: 2015 Volume: 88

Year: 2014 Volume: 87

Year: 2013 Volume: 86

Year: 2012 Volume: 85

Year: 2012 Volume: 85 Spec No 1

Year: 2011 Volume: 84

Year: 2011 Volume: 84 Spec No 1

Year: 2011 Volume: 84 Spec No 2

Conventional MRI evaluation of gliomas.

Dynamic contrast-enhanced imaging techniques: CT and MRI.

Methodology of diffusion-weighted, diffusion tensor and magnetisation transfer imaging.

Imaging biomarkers of angiogenesis and the microvascular environment in cerebral tumours.

Imaging hypoxia in gliomas

Imaging biomarkers of brain tumour margin and tumour invasion.

Specific biomarkers of receptors, pathways of inhibition and targeted therapies: pre-clinical developments.

Specific biomarkers of receptors, pathways of inhibition and targeted therapies: clinical applications.

Clinical applications of imaging biomarkers. Part 2. The neurosurgeon's perspective.

Clinical applications of imaging biomarkers. Part 3. The neuro-oncologist's perspective.

Multicentre imaging measurements for oncology and in the brain

Diagnosis and treatment in neuro-oncology: an oncological perspective.

Biology, genetics and imaging of glial cell tumours.

The changing face of brain tumours. Preface.

Year: 2011 Volume: 84 Spec No 3

Year: 2010 Volume: 83

Year: 2009 Volume: 82

Year: 2008 Volume: 81

Year: 2008 Volume: 81 Spec No 1

Year: 2007 Volume: 80

Year: 2007 Volume: 80 Spec No 2

Diagnosis and treatment in neuro-oncology: an oncological perspective.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Rees, J. H.
Description	Country affiliation: United kingdom Author Affiliation: Rees JH ( UCL Institute of Neurology and National Hospital for Neurology and Neurosurgery, Queen Square, London, UK. j.rees@ion.ucl.ac.uk)
Abstract	Although brain tumours are rare compared with other malignancies, they are responsible, in many cases, for severe physical and cognitive disability and have a high case fatality rate (13% overall survival at 5 years). Gliomas account for over 60% of primary brain tumours and usually present with one or more symptoms of raised intracranial pressure, progressive neurological deficit, seizures, focal or global cognitive decline. The diagnosis is made by a combination of imaging and histological examination of tumour specimen. Contrast-enhanced MRI is the gold standard imaging modality and provides highly sensitive anatomical information about the tumour. Advanced imaging modalities provide complementary information about brain tumour metabolism, blood flow and ultrastructure and are being increasingly incorporated into routine clinical sequences. Imaging is essential for guiding surgery and radiotherapy treatments and for monitoring response to, and progression of, therapy. However, changes in imaging over time may be misinterpreted and lead to incorrect assumptions about the effectiveness of treatments. Thus, the disappearance of contrast enhancement and resolution of oedema after anti-angiogenesis treatments is seen early while conventional T(2) weighted/FLAIR sequences demonstrate continual tumour growth (pseudoregression). Conversely imaging may suggest lack of efficacy of treatment e.g. increasing tumour size and contrast enhancement following chemoradiation for malignant gliomas (pseudoprogression), which then stabilise or resolve after a few months of continued treatment and that paradoxically may be associated with a better outcome. These factors have led to a re-evaluation of the role of standard sequences in the assessment of treatment response spurning interest in the development of quantitative biomarkers.
File Format	HTM / HTML
ISSN	00071277
DOI	10.1259/bjr/18061999
Journal	The British Journal of Radiology
Volume Number	84 Spec No 2
Language	English
Publisher	BIR Publications
Publisher Date	2011-12-01
Publisher Place	Great Britain (UK)
Access Restriction	Open
Subject Keyword	Therapy Image Enhancement Brain Neoplasms Medical Oncology Magnetic Resonance Imaging Contrast Media Glioma Diagnosis Discipline Radiology
Content Type	Text
Resource Type	Article

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in