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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Suzuki, Kentaro Aoki, Junya Sakamoto, Yuki Kanamaru, Takuya Abe, Arata Suda, Satoshi Okubo, Seiji Kimura, Kazumi |
| Description | Author Affiliation: Suzuki K ( Department of Neurological Science, Nippon Medical School Hospital, Tokyo, Japan. Electronic address: kentarow@nms.ac.jp.); Aoki J ( Department of Neurological Science, Nippon Medical School Hospital, Tokyo, Japan.); Sakamoto Y ( Department of Neurological Science, Nippon Medical School Hospital, Tokyo, Japan.); Kanamaru T ( Department of Neurological Science, Nippon Medical School Hospital, Tokyo, Japan.); Abe A ( Department of Neurological Science, Nippon Medical School Hospital, Tokyo, Japan.); Suda S ( Department of Neurological Science, Nippon Medical School Hospital, Tokyo, Japan.); Okubo S ( Department of Neurological Science, Nippon Medical School Hospital, Tokyo, Japan.); Kimura K ( Department of Neurological Science, Nippon Medical School Hospital, Tokyo, Japan.) |
| Abstract | OBJECTIVE: This study was performed to investigate whether the Penumbra 5MAX ACE is superior to other Penumbra systems. MATERIALS AND METHODS: We performed a retrospective, single center analysis of patients with acute ischemic stroke with occlusion of the internal carotid artery or middle cerebral artery (M1 segment) who underwent endovascular therapy using a Penumbra system. The reperfusion success rate, puncture-to-revascularization time, and number of passes were assessed. Multivariate regression analysis was conducted to evaluate independent factors related to revascularization within 60 minutes. Successful revascularization was defined by a thrombolysis in cerebral infarction score ≥2b. RESULTS: The Penumbra 5MAX ACE was used in 24 of the 40 patients (60%). Although the revascularization success rate was similar between patient groups (P = .229), the number of passes was significantly lower (1.5 ± .8 versus 2.6 ± 1.3, P = .006) and the puncture-to-revascularization time was shorter (50 ± 26 minutes versus 116 ± 69 minutes, P = .002) in patients treated with the Penumbra 5MAX ACE. The Penumbra 5MAX ACE was identified as an independent factor for early revascularization (odds ratio, 5.80; P = .041). Among patients with a premorbid modified Rankin Scale score of 0-1, a modified Rankin Scale score of 0-2 at 3 months was observed in 15 of the 19 patients (79%) treated with the Penumbra 5MAX ACE and in 8 of the 16 (50%) who were not (P = .072). CONCLUSION: Acute revascularization therapy using the Penumbra 5MAX ACE can achieve rapid successful recanalization and tend to improve clinical outcomes. |
| File Format | HTM / HTML |
| ISSN | 10523057 |
| Issue Number | 12 |
| Journal | Journal of Stroke and Cerebrovascular Diseases |
| Volume Number | 25 |
| e-ISSN | 15328511 |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2016-12-01 |
| Publisher Place | United States |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Cardiology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Rehabilitation Neurology (clinical) Surgery Cardiology and Cardiovascular Medicine |
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