NDLI: Detection of novel divergent arenaviruses in boid snakes with inclusion body disease in The Netherlands.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Bodewes, R. Kik, M. J. L. Raj, V. Stalin Schapendonk, C. M. E. Haagmans, B. L. Smits, S. L. Osterhaus, A. D. M. E.
Spatial Coverage	Netherlands
Description	Country affiliation: Netherlands Author Affiliation: Bodewes R ( Department of Viroscience, Erasmus Medical Centre, Dr Molewaterplein 50, Rotterdam, The Netherlands. r.bodewes@erasmusmc.nl)
Abstract	Arenaviruses are bi-segmented negative-stranded RNA viruses, which were until recently only detected in rodents and humans. Now highly divergent arenaviruses have been identified in boid snakes with inclusion body disease (IBD). Here, we describe the identification of a new species and variants of the highly divergent arenaviruses, which were detected in tissues of captive boid snakes with IBD in The Netherlands by next-generation sequencing. Phylogenetic analysis of the complete sequence of the open reading frames of the four predicted proteins of one of the detected viruses revealed that this virus was most closely related to the recently identified Golden Gate virus, while considerable sequence differences were observed between the highly divergent arenaviruses detected in this study. These findings add to the recent identification of the highly divergent arenaviruses in boid snakes with IBD in the United States and indicate that these viruses also circulate among boid snakes in Europe.
File Format	HTM / HTML
ISSN	00221317
Issue Number	Pt 6
Volume Number	94
e-ISSN	14652099
Journal	Journal of General Virology
Language	English
Publisher	Microbiology Society
Publisher Date	2013-06-01
Publisher Place	Great Britain (UK)
Access Restriction	Subscribed
Subject Keyword	Research Support, Non-u.s. Gov't Discipline Virology Isolation & Purification Molecular Sequence Data Viral Proteins Phylogeny Metabolism Snakes Journal Article Arenavirus Virology Inclusion Bodies, Viral Netherlands Animals Classification Genetics Arenaviridae Infections Veterinary Evolution, Molecular
Content Type	Text
Resource Type	Article
Subject	Virology

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