| Content Provider |
World Health Organization (WHO)-Global Index Medicus |
| Author |
Xiao, Songshu Wan, Yajun Xue, Min Zeng, Xiangyang Xiao, Fang Xu, Dabao Yang, Xi Zhang, Pu Sheng, Wen Xu, Junlei Zhou, Sai |
| Description |
Country affiliation: China Author Affiliation: Xiao S ( Department of Obstetrics and Gynecology, Third Xiangya Hospital, Central South University, Changsha, China.); Wan Y ( Department of Obstetrics and Gynecology, Third Xiangya Hospital, Central South University, Changsha, China.); Xue M ( Department of Obstetrics and Gynecology, Third Xiangya Hospital, Central South University, Changsha, China. Electronic address: 287932636@qq.com.); Zeng X ( Department of Obstetrics and Gynecology, Third Xiangya Hospital, Central South University, Changsha, China.); Xiao F ( Department of Obstetrics and Gynecology, Third Xiangya Hospital, Central South University, Changsha, China.); Xu D ( Department of Obstetrics and Gynecology, Third Xiangya Hospital, Central South University, Changsha, China.); Yang X ( Department of Obstetrics and Gynecology, Third Xiangya Hospital, Central South University, Changsha, China.); Zhang P ( Department of Obstetrics and Gynecology, Third Xiangya Hospital, Central South University, Changsha, China.); Sheng W ( Department of Obstetrics and Gynecology, Third Xiangya Hospital, Central South University, Changsha, China.); Xu J ( Department of Obstetrics and Gynecology, Third Xiangya Hospital, Central South University, Changsha, China.); Zhou S ( Department of Obstetrics and Gynecology, Third Xiangya Hospital, Central South University, Changsha, China.) |
| Abstract |
OBJECTIVE: To analyze data from the hysteroscopic adhesiolysis of moderate-to-severe intrauterine adhesions (IUAs), and to review the disease etiology, changes in menstruation, uterine recovery, and reproductive prognosis of women after comprehensive therapy. METHODS: In a retrospective descriptive analysis, clinical data were assessed from 683 patients with moderate-to-severe IUAs who were treated by hysteroscopic adhesiolysis at Third Xiangya Hospital, Changsha, China, between January 2007 and December 2011. Patients underwent comprehensive treatment. After hysteroscopic adhesiolysis, a persistent balloon urinary catheter was inserted, together with an intrauterine device (IUD). Intrauterine sodium hyaluronate gel was injected to prevent adhesion reformation, and oral estrogen was administered to promote endometrial regeneration. The outcomes were menstrual changes and uterine recovery under hysteroscopy, and the reproductive prognosis of patients with fertility intentions. RESULTS: At the 3-month follow-up, the postoperative recovery of uterine shape was better than the recovery of menstruation among patients with moderate-to-severe IUAs. Among the 475 patients with fertility intentions, the pregnancy and live birth rates were 66.1% (314/475) and 64.0% (201/314), respectively. CONCLUSION: Comprehensive treatment prevented the recurrence of IUAs to a certain extent, but some severe endometrial injuries were found to be irreparable, reducing the rate of subsequent pregnancy and live birth. |
| File Format |
HTM / HTML |
| ISSN |
00207292 |
| Issue Number |
2 |
| Volume Number |
125 |
| e-ISSN |
18793479 |
| Journal |
International Journal of Gynecology & Obstetrics |
| Language |
English |
| Publisher |
Wiley-Blackwell |
| Publisher Date |
2014-05-01 |
| Publisher Place |
Ireland |
| Access Restriction |
One Nation One Subscription (ONOS) |
| Subject Keyword |
Hysteroscopy Therapy Device Removal Hyaluronic Acid Humans Discipline Obstetrics Secondary Prevention Journal Article Abortion, Induced Young Adult Intrauterine Devices Uterine Diseases Etiology Adult Female Physiology Retrospective Studies Severity Of Illness Index Pregnancy Rate Adverse Effects Menstruation Adjuvants, Immunologic Complications Live Birth Uterine Balloon Tamponade Combined Modality Therapy Tissue Adhesions Therapeutic Use Pregnancy Tuberculosis Recovery Of Function Discipline Gynecology |
| Content Type |
Text |
| Resource Type |
Article |
| Subject |
Obstetrics and Gynecology |
