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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Dinis-Oliveira, Ricardo Jorge Carvalho, Félix Duarte, José Alberto Dias, Ricardo Magalhães, Teresa Santos, Agostinho |
| Description | Country affiliation: Portugal Author Affiliation: Dinis-Oliveira RJ ( Faculty of Medicine, University of Porto, Porto, Portugal. ricardinis@sapo.pt) |
| Abstract | Psychiatric deviations resulting from alcohol and illegal drug abuse may be considered a major risk factor for suicidal behavior. This report describes a suicide by hanging, under the influence of ketamine and alcohol. The victim was a 29-year-old man, found dead hanging by the neck from a metallic beam in the ceiling of his workplace. Besides characteristic signs of hanging seen at the autopsy, toxicological analysis revealed a femoral blood concentration of ketamine and ethanol of 1.3mg/L and 0.66g/L, respectively. Positive qualitative results for ketamine were also detected, in a powder found near the victim and on the victim's nostrils, which suggests nasal inhaling as administration route. The hallucinogenic effects caused by ketamine, associated with an increased sensitivity of N-methyl-d-aspartate (NMDA) receptors to ketamine as result of the previous history of alcoholism should be considered as potential inducing factors in suicide behaviors. |
| File Format | HTM / HTML |
| ISSN | 03790738 |
| Issue Number | 1-3 |
| Volume Number | 202 |
| e-ISSN | 18726283 |
| Journal | Forensic Science International |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2010-10-10 |
| Publisher Place | Ireland |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Forensic Science Research Support, Non-u.s. Gov't Adverse Effects Ethanol Complications Carotid Artery Injuries Humans Gas Chromatography-mass Spectrometry Neck Injuries Male Forensic Toxicology Asphyxia Suicide Blood Journal Article Case Reports Pathology Ketamine Central Nervous System Depressants Substance-related Disorders Carotid Artery, Common Adult Forensic Pathology Anesthetics, Dissociative |
| Content Type | Text |
| Resource Type | Case study Article |
| Subject | Law Pathology and Forensic Medicine |
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