NDLI: Toxicity of dietary methylmercury to fish: derivation of ecologically meaningful threshold concentrations.

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Toxicity of dietary methylmercury to fish: derivation of ecologically meaningful threshold concentrations.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Depew, David C. Basu, Niladri Burgess, Neil M. Campbell, Linda M. Devlin, Ed W. Drevnick, Paul E. Hammerschmidt, Chad R. Murphy, Cheryl A. Sandheinrich, Mark B. Wiener, James G.
Description	Country affiliation: Canada Author Affiliation: Depew DC ( Department of Biology and School of Environmental Studies, Queen's University, Kingston, Ontario, Canada. depewd@gmail.com)
Abstract	Threshold concentrations associated with adverse effects of dietary exposure to methylmercury (MeHg) were derived from published results of laboratory studies on a variety of fish species. Adverse effects related to mortality were uncommon, whereas adverse effects related to growth occurred only at dietary MeHg concentrations exceeding 2.5 µg g(-1) wet weight. Adverse effects on behavior of fish had a wide range of effective dietary concentrations, but generally occurred above 0.5 µg g(-1) wet weight. In contrast, effects on reproduction and other subclinical endpoints occurred at dietary concentrations that were much lower (<0.2 µg g(-1) wet wt). Field studies generally lack information on dietary MeHg exposure, yet available data indicate that comparable adverse effects have been observed in wild fish in environments corresponding to high and low MeHg contamination of food webs and are in agreement with the threshold concentrations derived here from laboratory studies. These thresholds indicate that while differences in species sensitivity to MeHg exposure appear considerable, chronic dietary exposure to low concentrations of MeHg may have significant adverse effects on wild fish populations but remain little studied compared to concentrations in mammals or birds.
File Format	HTM / HTML
ISSN	07307268
Issue Number	7
Volume Number	31
e-ISSN	15528618
Journal	Environmental Toxicology and Chemistry
Language	English
Publisher	Wiley
Publisher Date	2012-07-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Research Support, Non-u.s. Gov't Ecotoxicology Toxicity Discipline Environmental Health Discipline Toxicology Ecology No-observed-adverse-effect Level Drug Effects Methylmercury Compounds Journal Article Growth & Development Food Chain Reproduction Animals Diet Fishes Discipline Chemistry Physiology
Content Type	Text
Resource Type	Article
Subject	Environmental Chemistry Health, Toxicology and Mutagenesis

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