NDLI: Epidemiologic characteristics, clinical manifestations, and risk factors of 139 patients with Ebola virus disease in western Sierra Leone.

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Epidemiologic characteristics, clinical manifestations, and risk factors of 139 patients with Ebola virus disease in western Sierra Leone.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Xu, Zhe Jin, Bo Teng, Guangju Rong, Yihui Sun, Lijian Zhang, Jian Du, Ning Liu, Liming Su, Haibin Yuan, Yue Chen, Haoyang
Description	Country affiliation: China Author Affiliation: Xu Z ( Treatment and Research Center for Infectious Diseases, 302 Hospital of PLA, Beijing, China.); Jin B ( Treatment and Research Center for Liver Cirrhosis, 302 Hospital of PLA, Beijing, China.); Teng G ( Treatment and Research Center for Non-Infectious Liver Diseases, 302 Hospital of PLA, Beijing, China.); Rong Y ( Treatment and Research Center for Liver Tumor, 302 Hospital of PLA, Beijing, China.); Sun L ( Intensive Care Unit, 302 Hospital of PLA, Beijing, China.); Zhang J ( Radiotherapy Center for Liver Tumor, 302 Hospital of PLA, Beijing, China.); Du N ( Chinese and Western Medicine Combined for Liver Disease Diagnosis and Treatment Center, 302 Hospital of PLA, Beijing, China.); Liu L ( Center for Clinical Laboratory, 302 Hospital of PLA, Beijing, China.); Su H ( Treatment and Research Center for Liver Failure, 302 Hospital of PLA, Beijing, China.); Yuan Y ( Department of Infection Control, 302 Hospital of PLA, Beijing, China.); Chen H ( Department of Medical Affairs, 302 Hospital of PLA, Beijing, China. Electronic address: chenhaoyang302@126.com.)
Abstract	OBJECTIVE: We aimed to fully describe epidemiologic characteristics, clinical manifestations, and clinical outcomes of Ebola virus disease (EVD), as well as detect independent factors significantly associated with mortality of the disease. METHODS: One hundred thirty-nine confirmed EVD patients enrolled at the JUI Holding and Treatment Centre in western Sierra Leone between November 15, 2014, and January 18, 2015, and demographic and clinical data were retrospectively collected and analyzed. RESULTS: The median age of investigated patients was 29 years and 55.4% were women. Of them, 76 patients (54.7%) died and 63 patients (45.3%) were cured. Case fatality rate among male patients was higher than in female patients (69.4% vs 42.9%). Fatigue (82.0%), anorexia (70.5%), abdominal pain (59.7%), diarrhea (58.3%), vomiting (56.1%), fever (55.4%), and muscle pain (54.0%) were the most common symptoms. In addition, 55.4% of investigated patients reported fever. Bleeding was seen in 10.8% of patients. CONCLUSIONS: Our data show that mortality of EVD is associated with an older age, fever, and probably hiccups.
File Format	HTM / HTML
ISSN	01966553
Issue Number	11
Journal	American Journal of Infection Control
Volume Number	44
e-ISSN	15273296
Language	English
Publisher	Elsevier
Publisher Date	2016-11-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Communicable Diseases
Content Type	Text
Resource Type	Article
Subject	Infectious Diseases Public Health, Environmental and Occupational Health Epidemiology Health Policy

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