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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Cutrell, James B. Barros, Nicolas McBroom, Mandy Luby, James Minhajuddin, Abu Ring, W. Steves Greilich, Philip E. |
| Description | Author Affiliation: Cutrell JB ( University of Texas Southwestern Medical Center, Dallas, TX); Barros N ( University of Texas Southwestern Medical Center, Dallas, TX); McBroom M ( University of Texas Southwestern Medical Center, Dallas, TX.); Luby J ( University of Texas Southwestern Medical Center, Dallas, TX); Minhajuddin A ( University of Texas Southwestern Medical Center, Dallas, TX.); Ring WS ( University of Texas Southwestern Medical Center, Dallas, TX.); Greilich PE ( University of Texas Southwestern Medical Center, Dallas, TX. Electronic address: philip.greilich@UTSouthwestern.edu.) |
| Abstract | BACKGROUND: Deep sternal wound infection (DSWI) following cardiac surgery is a serious complication, but risk factors associated with DSWI have not been fully elucidated. METHODS: We analyzed all DSWI cases at our institution from 2010-2013 in adult cardiac median sternotomy cases, based on Society of Thoracic Surgeons or National Healthcare Safety Network definitions, but with 1-year surveillance postsurgery. Controls were matched 3:1 per case for procedure, age, and year of surgery. Demographic and operative data were pulled from Society of Thoracic Surgeons database and chart review. Potential variables were evaluated using univariate and multivariate conditional logistic regression. RESULTS: Out of 1,894 surgeries performed, 39 DSWI cases (2%) and 117 controls were identified. In univariate analyses, patients with red blood cell (RBC) transfusion ≥ 4 units, any platelet transfusion, previous infections, and chronic infections were associated with higher DSWI. RBC transfusion ≥ 4 units (P = .037) and chronic infections (P = .029) remained significant risk factors for DSWI in multivariate analysis. Preoperative anemia alone was not associated with more DSWI, but its interaction with RBC transfusion ≥ 4 units was significant. CONCLUSIONS: High-volume RBC transfusions and chronic infections were strongly associated with DSWI in our population and represent potentially modifiable areas for improvement. |
| File Format | HTM / HTML |
| ISSN | 01966553 |
| Issue Number | 11 |
| Journal | American Journal of Infection Control |
| Volume Number | 44 |
| e-ISSN | 15273296 |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2016-11-01 |
| Publisher Place | United States |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Communicable Diseases |
| Content Type | Text |
| Resource Type | Article |
| Subject | Infectious Diseases Public Health, Environmental and Occupational Health Epidemiology Health Policy |
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