NDLI: Protective effects of zinc-bearing clinoptilolite on broilers challenged with Salmonella pullorum.

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Protective effects of zinc-bearing clinoptilolite on broilers challenged with Salmonella pullorum.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Wang, L. C. Zhang, T. T. Wen, C. Jiang, Z. Y. Wang, T. Zhou, Y. M.
Description	Author Affiliation: Wang LC ( College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, PR China.)
Abstract	This study was conducted to evaluate the effects of zinc-bearing clinoptilolite (ZnCP) on broilers challenged with Salmonella pullorum for a 21-d feeding trial. A total of 240 one-day-old chickens was allocated into 4 treatment groups: 1) nonchallenged control (CON) fed basal diet; 2) S. pullorum-challenged control (SCC) fed basal diet; 3) Salmonella challenge fed basal diet plus antibiotic (ANT); 4) Salmonella challenge fed basal diet plus 0.2% ZnCP (ZnCP). Compared with CON, Salmonella challenge caused adverse effects on ADG (P<0.05), ADFI, feed/gain ratio in broilers, Salmonella and Lactobacillus colonies at 7 d (P<0.05) and 21 d, and serum diamine oxidase (DAO) activity. Moreover, the relative weight of spleen of 21-d birds, malondialdehyde (MDA) content of jejunual and ileal mucosa at 21 d, and the superoxide dismutase (SOD) activity of ileal mucosa were also significantly negatively affected by SCC treatment (P<0.05). Supplementation of ZnCP in basal diet significantly improved ADG and reduced Salmonella colonies in cecal contents and serum DAO activity both at 7 and 21 d (P<0.05), compared with SCC. Furthermore, supplementation with ZnCP as well as ANT signiï¬cantly decreased the relative weight of spleen at 21 d, reduced MDA contents of jejunual and ileal mucosa at 21 d (P<0.05), and improved the SOD activity of ileal mucosa at 7 d as compared with SCC (P<0.05). The results suggested that ZnCP addition in feed exerted protective effects on performance and gut health of broilers against S. pullorum infection.
File Format	HTM / HTML
ISSN	00325791
e-ISSN	15253171
Journal	Poultry Science
Issue Number	8
Volume Number	91
Language	English
Publisher	Oxford University Press
Publisher Date	2012-08-01
Publisher Place	Great Britain (UK)
Access Restriction	Open
Subject Keyword	Discipline Veterinary Medicine Salmonella Infections, Animal Prevention & Control Salmonella Classification Zeolites Chemistry Pharmacology Zinc Amine Oxidase (copper-containing) Blood Metabolism Animal Feed Animals Anti-bacterial Agents Antioxidants Diet Veterinary Intestinal Mucosa Lymphoid Tissue Anatomy & Histology Drug Effects Poultry Diseases Randomized Controlled Trial
Content Type	Text
Resource Type	Article
Subject	Medicine Animal Science and Zoology

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