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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Walia, Mayanka Rawat, Kiran Bhushan, Shashi Padwad, Yogendra S. Singh, Bikram |
| Spatial Coverage | India |
| Description | Country affiliation: India Author Affiliation: Walia M ( Academy of Scientific and Innovative Research, CSIR-Institute of Himalayan Bioresource Technology, Palampur, Himachal Pradesh, 176061, India) |
| Abstract | BACKGROUND: Apple pomace is generated in huge quantities in juice-processing industries the world over and continuous efforts are being made for its inclusive utilization. In this study, apple seeds separated from industrial pomace were used for extraction of oil. The fatty acid composition, physicochemical and antioxidant as well as in vitro anticancer properties of extracted oil were studied to assess its suitability in food and therapeutic applications. RESULTS: The fatty acid composition of seed oil revealed the dominance of oleic (46.50%) and linoleic acid (43.81%). It had high iodine (121.8 g I 100 g⻹) and saponification value (184.91 mg KOH g⻹ oil). The acid value, refractive index and relative density were 4.28 mg KOH g⻹, 1.47 and 0.97 mg mL⻹, respectively. The antioxidant potential (IC50) of apple seed oil was 40.06 µg mL⻹. Cytotoxicity of apple seed oil against CHOK1, SiHa and A549 cancer cell lines ranged between 0.5 ± 0.06% and 88.6 ± 0.3%. CONCLUSION: The physicochemical properties of apple seed oil were comparable with edible food oil, indicating its better stability and broad application in the food and pharmaceutical industries. Apple seed oil could be a good source of natural antioxidants. Also, the in vitro cytotoxic activity against specific cell lines exhibited its potential as an anticancer agent. |
| File Format | HTM / HTML |
| ISSN | 00225142 |
| Issue Number | 5 |
| Volume Number | 94 |
| e-ISSN | 10970010 |
| Journal | Journal of the Science of Food and Agriculture |
| Language | English |
| Publisher | Wiley |
| Publisher Date | 2014-03-30 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Agriculture Antineoplastic Agents, Phytogenic Isolation & Purification Antioxidants Fatty Acids Analysis Industrial Waste Malus Chemistry Plant Oils Seeds Animals Adverse Effects Economics Pharmacology Cho Cells Cell Line, Tumor Cell Proliferation Drug Effects Chemical Phenomena Cricetulus Dietary Supplements Fatty Acids, Nonesterified Food Preservatives Food-processing Industry Fruit Humans India Linoleic Acid Oleic Acid Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nutrition and Dietetics Food Science Biotechnology Agronomy and Crop Science |
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