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Bevacizumab used for the treatment of severe, refractory perilesional edema due to an arteriovenous malformation treated with stereotactic radiosurgery.

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Bevacizumab used for the treatment of severe, refractory perilesional edema due to an arteriovenous malformation treated with stereotactic radiosurgery.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Williams, Brian J. Park, Deric M. Sheehan, Jason P.
Description	Country affiliation: United States Author Affiliation: Williams BJ ( Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA.)
Abstract	The authors present a case of an arteriovenous malformation of the central sulcus treated with Gamma Knife surgery. The patient developed perilesional edema 9 months after treatment and experienced severe headache and hemiparesis. Her symptoms were refractory to corticosteroid therapy and pain management. She was subsequently treated with bevacizumab with striking improvement in her symptoms and results of neuroimaging studies. This is the first time that bevacizumab has been used to control severe refractory perilesional edema related to an intracranial arteriovenous malformation.
File Format	HTM / HTML
ISSN	00223085
e-ISSN	19330693
Journal	Journal of Neurosurgery
Issue Number	5
Volume Number	116
Language	English
Publisher	American Association of Neurological Surgeons
Publisher Date	2012-05-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Discipline Neurosurgery Angiogenesis Inhibitors Therapeutic Use Antibodies, Monoclonal, Humanized Brain Edema Drug Therapy Etiology Intracranial Arteriovenous Malformations Complications Surgery Postoperative Complications Radiosurgery Adverse Effects Angiography, Digital Subtraction Bevacizumab Headache Image Processing, Computer-assisted Magnetic Resonance Imaging Paresis Steroids Tomography, X-ray Computed
Content Type	Text
Resource Type	Case study Article
Subject	Neurology (clinical) Surgery

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