NDLI: Breast cancer survival among economically disadvantaged women: the influences of delayed diagnosis and treatment on mortality.

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Breast cancer survival among economically disadvantaged women: the influences of delayed diagnosis and treatment on mortality.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Smith, Emily Rose Adams, Swann Arp Das, Irene Prabhu Bottai, Matteo Fulton, Jeanette Hebert, James R.
Spatial Coverage	South Carolina
Description	Country affiliation: United States Author Affiliation: Smith ER ( Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, USA. esmith@swmail.sw.org)
Abstract	Breast cancer affects thousands each year in the United States, and disproportionately affects certain subgroups. For example, the incidence of breast cancer in South Carolina is lower in African American compared with European American women by approximately 12% to 15%, but their mortality rate is twice as high as in European American women. The purpose of the study was to assess factors associated with breast cancer mortality between African American and European American women. Participants (n=314) in South Carolina's Breast and Cervical Cancer Early Detection Program (SCBCCEDP), which provides breast cancer screening and treatment services, during the years 1996-2004 were included in the study. Data, including tumor characteristics, delay intervals, and race, were examined using the chi(2) test and the Wilcoxon rank-sum test. Cox regression modeling was used to assess the relationship between delay intervals and other factors. No racial differences were found in age at diagnosis, tumor characteristics, or delay intervals. Time delay intervals did not explain differences and mortality rates by race. Survival, however, was affected by prognostic factors as well as by a significant interaction between hormone-receptor status and race. Despite the excellent record of the SCBCCEDP in screening and diagnostic or treatment referrals, the racial disparities in breast cancer mortality continue to exist in South Carolina. These findings highlight the need for future research into the etiology of racial differences, and their impact on breast cancer survival.
File Format	HTM / HTML
ISSN	10559965
e-ISSN	15387755
DOI	10.1158/1055-9965.EPI-08-0221
Journal	Cancer Epidemiology Biomarkers & Prevention
Issue Number	10
Volume Number	17
Language	English
Publisher	American Association for Cancer Research
Publisher Date	2008-10-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Discipline Cancer epidemiology African Americans Statistics & Numerical Data Breast Neoplasms Mortality European Continental Ancestry Group Health Services Accessibility Chi-square Distribution Proportional Hazards Models Registries Socioeconomic Factors South Carolina Epidemiology Statistics, Nonparametric Survival Analysis Time Factors Research Support, N.i.h., Extramural Research Support, U.s. Gov't, P.h.s.
Content Type	Text
Resource Type	Article
Subject	Epidemiology Oncology

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