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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Castedal, M. Andersson, M. Polanska-Tamborek, D. Friman, S. Olausson, M. Fehrman-Ekholm, I. |
| Description | Country affiliation: Sweden Author Affiliation: Castedal M ( The Transplant Institute, Sahlgrenska University Hospital, Göteborg, Sweden. maria.castedal@medfak.gu.se) |
| Abstract | OBJECTIVES: At our center living donor liver transplantation (LDLT) represents 4% of all transplantations. The aim of this cross-sectional study was to clarify the current well-being of the donors, their experiences of being a donor, as well as the regenerative capacity of the liver. PATIENTS AND METHOD: Thirty-six healthy subjects donated a part of their liver between 1996 and 2007. Thirty-four patients participated in the study and completed our questionnaire. We performed magnetic resonance imaging (MRI) of the liver, physical examination, and blood chemistry. RESULTS: Twenty-three subjects had donated the left lateral segment and 11 the right lobe. Their hospital stay ranged from 5-15 days (median, 10). Mostly, the sick-leave period was 8-12 weeks and time for recovery was 3-6 months. Long-term problems were heartburn, abdominal discomfort, incisional hernia, and fatigue. Twenty-six (76.5%) subjects viewed the donation experience as entirely positive; no one was regretful. Liver function tests were normal. The MRI data at follow-up of 13 left lateral segment and 11 right lobe grafts showed recovery of the total liver volume to almost preoperative values, mean 1522 ± 241 mL versus 1552 ± 219 mL, respectively. CONCLUSION: Living liver donors commonly recovered after 3-6 months, perceiving donation as a positive experience with no regret. Durable side effects were mainly heartburn and abdominal discomfort, but the symptoms were mostly mild. Liver function was normal. The MRI data showed a mean regeneration of liver volume to 98.6% of the preoperative values. |
| File Format | HTM / HTML |
| ISSN | 00411345 |
| Issue Number | 10 |
| Volume Number | 42 |
| e-ISSN | 18732623 |
| Journal | Transplantation Proceedings |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2010-12-01 |
| Publisher Place | United States |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Transplantation__semicolon__medicine Liver Transplantation Living Donors Blood Chemical Analysis Follow-up Studies Humans Magnetic Resonance Imaging Physical Examination Journal Article |
| Content Type | Text |
| Resource Type | Article |
| Subject | Transplantation Surgery |
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