NDLI: Samtidig bruk av ulike benzodiazepiner.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Handal, Marte Skurtveit, Svetlana Mørland, Jørg G.
Spatial Coverage	Norway
Description	Country affiliation: Norway Author Affiliation: Handal M ( Avdeling for legemiddelepidemiologi, Divisjon for epidemiologi, Nasjonalt folkehelseinstitutt, Norway. marte.handal@fhi.no)
Abstract	BACKGROUND: The various benzodiazepines have essentially the same mechanism of action and differ from one another primarily through differences in pharmacokinetics. There is no pharmacological basis for using more than one benzodiazepine for the same patient. The purpose of the study was to examine the occurence of co-medication with different types of benzodiazepines in Norway. MATERIAL AND METHOD: Data were obtained from the Norwegian Prescription Database. Patients who received at least one benzodiazepine in 2008 were included (n = 299,185). The percentage of users who were co-medicated with at least two different benzodiazepines and the amounts prescribed were calculated and stratified by gender and age. RESULTS: It is highly probably that 27,861 (14,6%) of patients who received at least two benzodiazepines in the course of 2008 used two different benzodiazepines simultaneously. 13,267 (6.9%) of the patients were prescribed at least two different benzodiazepines on the same prescription. A larger number of women were co-medicated with different benzodiazepines, but the proportion of comedication was higher in men than in women, and most frequent in the age group 18-49 years. INTERPRETATION: There is an extensive and unfortunate prescription practice whereby the same patient is prescribed different benzodiazepines that are used concurrently. Patients who use different benzodiazepines concurrently are mainly prescribed these by one and the same doctor.
File Format	HTM / HTML
ISSN	00292001
e-ISSN	08077096
Journal	Tidsskrift for Den norske legeforening
Issue Number	5
Volume Number	132
Language	Norwegian
Publisher	Norwegian Medical Association
Publisher Date	2012-03-06
Publisher Place	Norway
Access Restriction	Open
Subject Keyword	Discipline Medicine Anti-anxiety Agents Administration & Dosage Anticonvulsants Benzodiazepines Hypnotics And Sedatives Adolescent Pharmacokinetics Drug Interactions Drug Prescriptions Statistics & Numerical Data Drug Therapy, Combination Norway Physician's Practice Patterns Registries
Alternative Title	Co-medication with benzodiazepines
Content Type	Text
Resource Type	Article
Subject	Medicine

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