NDLI: Utlevering av benzodiazepiner og z-hypnotika fra norske apotek 2004-11.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Bjørner, Trine Tvete, Ingunn Fride Aursnes, Ivar Skomedal, Tor
Spatial Coverage	Norway
Abstract	BACKGROUND: In Norway, total sales of benzodiazepines and Z drugs (zopiclone and zolpidem) have increased since the mid-1990s. On the basis of data from the Norwegian Prescription Database, we have studied the choice of medications and patterns of use in various gender and age groups. MATERIAL AND METHOD: Numbers for redemptions of benzodiazepines and Z drugs in Norwegian pharmacies for the years 2004-2011 were collected from the Prescription Registry. Population figures were collected from Statistics Norway. Consumption was calculated by the number of DDDs (defined daily doses). RESULTS: Among those who were supplied with benzodiazepines or Z drugs, recipients of more than 2 DDDs per day (heavy users) accounted for a small group. We registered an extensive use of Z drugs among older women, many of whom were prescribed an amount corresponding to a regular daily use of 1-2 DDDs. The total prescription of alprazolam and nitrazepam/flunitrazepam was minor, but high dosages were not uncommon among those who were prescribed these drugs. Only a small proportion of the patients who were prescribed clonazepam received a reimbursable prescription. The prescribing of a number of benzodiazepines and Z drugs at the same time remains not uncommon. INTERPRETATION: Prescribing of Z drugs to the elderly, and to women in particular, may indicate that many people in this group are regular users of sedative hypnotics, which is contrary to the guidelines. A considerable proportion of the prescriptions for clonazepam are outside of the approved indications. Among the users of the drugs studied, only a small fraction were heavy users, but since the use is widespread, this represents a considerable number of individuals.
File Format	HTM / HTML
ISSN	00292001
e-ISSN	08077096
Journal	Tidsskrift for Den norske legeforening
Issue Number	20
Volume Number	133
Language	Norwegian
Publisher	Norwegian Medical Association
Publisher Date	2013-10-29
Publisher Place	Norway
Access Restriction	Open
Subject Keyword	Discipline Medicine Benzodiazepines Administration & Dosage Drug Prescriptions Statistics & Numerical Data Hypnotics And Sedatives Azabicyclo Compounds Clonazepam Norway Pharmaceutical Services Piperazines Practice Guidelines As Topic Pyridines Registries Sex Factors
Alternative Title	Dispensing of benzodiazepines and Z drugs by Norwegian pharmacies 2004-2011
Content Type	Text
Resource Type	Article
Subject	Medicine

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Samtidig bruk av ulike benzodiazepiner.

Samhandling mellom allmennleger og apotek ved korreksjon av resepter.

Bruk av benzodiazepiner og cannabis blant unge voksne.

Mye søvnplager--for mye hypnotika.

Zopiklon og krampeanfall.

Siteringsanalyse av vitenskapelige artikler fra norske helseforetak 2005-11.

Samhandling mellom fastlege og apotek.

Auch Z-Substanzen werden missbraucht.

Utdanning og legemiddelbruk.

Utlevering av benzodiazepiner og z-hypnotika fra norske apotek 2004-11.

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Samtidig bruk av ulike benzodiazepiner.

Samhandling mellom allmennleger og apotek ved korreksjon av resepter.

Bruk av benzodiazepiner og cannabis blant unge voksne.

Mye søvnplager--for mye hypnotika.

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Siteringsanalyse av vitenskapelige artikler fra norske helseforetak 2005-11.

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Utdanning og legemiddelbruk.

Utlevering av benzodiazepiner og z-hypnotika fra norske apotek 2004-11.