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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Ye, Nengsheng Li, Jian Gao, Chong Xie, Yali |
| Description | Author Affiliation: Ye N ( Department of Chemistry, Capital Normal University, Beijing, PR China. yenshcnu@126.com) |
| Abstract | A novel CE method was developed for the separation and determination of three main tropane alkaloids in Flos daturae with a capillary coated by graphene oxide (GO). The GO-coated capillary was characterized by SEM, energy dispersive X-ray spectroscopy, and Raman spectroscopy, and the results indicated that the inner surface of the capillary was partially coated by GO. A phosphate solution (40 mM, pH7.0) containing 20% v/v methanol and 30% v/v acetonitrile was used as the running buffer for the analysis of the atropine, scopolamine, and anisodamine. The linear ranges of atropine, scopolamine, and anisodamine was 0.5-200 µg/mL with satisfactory correlation coefficients (R(2)) > 0.9987, and this novel method provided an efficient separation for three tropane alkaloids as well as a good reproducibility and stability. Finally, the method was successfully applied for the determination of these three tropane alkaloids in plant extracts. |
| File Format | HTM / HTML |
| ISSN | 16159306 |
| Issue Number | 16 |
| Volume Number | 36 |
| e-ISSN | 16159314 |
| Journal | Journal of Separation Science |
| Language | English |
| Publisher | Wiley-VCH |
| Publisher Date | 2013-08-01 |
| Publisher Place | Germany |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Analytical Discipline Chemistry Atropine Chemistry Datura Electrophoresis, Capillary Methods Plant Extracts Scopolamine Hydrobromide Solanaceous Alkaloids Instrumentation Flowers Graphite Evaluation Studies Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Analytical Chemistry Filtration and Separation |
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