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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Nguyen, Charles Young, Simon Kretlow, James D. Mikos, Antonios G. Wong, Mark |
| Description | Country affiliation: United States Author Affiliation: Nguyen C ( Resident in Oral and Maxillofacial Surgery, Department of Oral and Maxillofacial Surgery, University of Texas Health Science Center at Houston, Houston, TX, USA.) |
| Abstract | PURPOSE: The purpose of the present study was to evaluate the effect of implant porosity on wound healing between solid and porous implants placed within a bony mandibular defect with intraoral exposure. MATERIALS AND METHODS: Solid poly(methyl methacrylate) (PMMA) implants similar to those used currently in clinical space maintenance applications in maxillofacial surgery were compared with poly(propylene fumarate) implants that contained a porous outer surface surrounding a solid core. A 10-mm diameter nonhealing bicortical defect with open communication into the oral cavity was created in the molar mandibular region of 12 adult male New Zealand white rabbits. Of the 12 rabbits, 6 received the hybrid poly(propylene fumarate) implants and 6 received the solid PMMA implants. At 12 weeks, the rabbit mandibles were harvested and sent for histologic staining and sectioning. RESULTS: Gross inspection and histologic examination showed all 6 poly(propylene fumarate) implants to be intact within the defect site at the termination of the study period, with 3 of the 6 specimens exhibiting a continuous circumferential soft tissue margin. In contrast, 5 of the 6 PMMA-implanted specimens were exposed intraorally with an incomplete cuff of soft tissue around the implant. One of the PMMA-implanted specimens exhibited complete extrusion and subsequent loss of the implant. Fisher's exact test was used to compare the occurrence of oral cavity wound healing between the 2 groups (P = .09). CONCLUSIONS: Although statistically significant differences between the 2 groups were not seen, our results have indicated that advantages might exist to using porous implants for space maintenance. Additional study is needed to evaluate these findings. |
| File Format | HTM / HTML |
| ISSN | 02782391 |
| Issue Number | 1 |
| Volume Number | 69 |
| e-ISSN | 15315053 |
| Journal | Journal of Oral and Maxillofacial Surgery |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2011-01-01 |
| Publisher Place | United States |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Medicine__semicolon__otorhinolaryngology__semicolon__surgery Biocompatible Materials Chemistry Mandibular Diseases Surgery Prostheses And Implants Prosthesis Design Animals Chemical Synthesis Connective Tissue Pathology Disease Models, Animal Edema Etiology Epithelium Fumarates Granulation Tissue Histiocytes Lymphocytes Male Mandible Materials Testing Mouth Mucosa Neutrophils Pilot Projects Polymethyl Methacrylate Polypropylenes Porosity Rabbits Surface Properties Surgical Wound Dehiscence Wound Healing Physiology Comparative Study Journal Article Research Support, N.i.h., Extramural |
| Content Type | Text |
| Resource Type | Article |
| Subject | Oral Surgery Otorhinolaryngology Surgery |
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