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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Ren, Jianming Li, Qing Dong, Fang Feng, Yan Guo, Zhanyong |
| Description | Country affiliation: China Author Affiliation: Ren J ( Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China.) |
| Abstract | In this work, two kinds of phenolic antioxidants-functionalized quaternized chitosan were synthesized in order to develop aqueous soluble antioxidant-polymer conjugates. Quaternized chitosan conjugated with gallic acid or caffeic acid was carried out and the antioxidant properties of the products (namely gallic acid-quaternized chitosan and caffeic acid-quaternized chitosan) against hydroxyl-radical, superoxide-radical and DPPH-radical were evaluated in vitro, respectively. The scavenging activities of the obtained gallic acid-quaternized chitosan and caffeic acid-quaternized chitosan exhibit a remarkable improvement over those of either chitosan or quaternized chitosan. And the scavenging effect indices of the products were all higher than 90% at a concentration of 1000 µg/mL. Because gallic acid-quaternized chitosan and caffeic acid-quaternized chitosan are convenient to prepare and possess improved potential activities, these materials may represent an attractive new platform for utilizations of chitosan. |
| File Format | HTM / HTML |
| ISSN | 01418130 |
| Volume Number | 53 |
| e-ISSN | 18790003 |
| Journal | International Journal of Biological Macromolecules |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2013-02-01 |
| Publisher Place | Netherlands |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Biochemistry Caffeic Acids Chemistry Chitosan Free Radical Scavengers Gallic Acid Biphenyl Compounds Chemical Synthesis Free Radicals Picrates Spectrophotometry, Ultraviolet Spectroscopy, Fourier Transform Infrared Superoxides Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Structural Biology Molecular Biology Biochemistry |
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