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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Kpodonu, Jacques Preventza, Ourania Ramaiah, Venkatesh G. Shennib, Hani Wheatley, Grayson H. Rodriquez-Lopez, Julio A. Williams, James Diethrich, Edward B. |
| Description | Country affiliation: United States Author Affiliation: Kpodonu J ( Arizona Heart Institute, Department of Cardiovascular and Endovascular Surgery, Phoenix, AZ, USA. jkpodonu@yahoo.com) |
| Abstract | BACKGROUND: To evaluate the feasibility and safety of thoracic endografting in the octogenarian population. METHODS: Between February 2000 and August 2005, 249 patients with a mean age of 69+/-12.3 years (range 23-91) underwent thoracic endografting. Forty-four patients (27 males and 17 females) were octogenarians with a mean age of 84+/-2.7 years. Indications for intervention included: atherosclerotic aneurysms (26/44, 59%), acute and chronic dissections (9/44, 20.5%), penetrating aortic ulcers (6/44, 14%) and contained rupture (3/44, 7%). RESULTS: Endovascular repair was achieved in all octogenarian patients (44/44, 100%). Mean length of stay was 4.7+/-3.6 days. Two cardiac-related deaths and 1 retrograde dissection death occurred (3/44, 7%). Complications included hemiparesis (n=2) with full recovery at discharge, groin hematoma (n=1), pneumonia (n=2) and stroke (n=1) [6/44, 11%]. Endoleaks were diagnosed in 3 patients [3/44, 7%] (2 type I, 1 type II) at 30-day follow-up. Two patients developed an endoleak beyond 30 days [2/44, 5%] (1 type I, 1 type II). Two re-interventions were necessary at 30 days (1 type I, 1 type II). Mean follow-up was 22 months and there were no device migrations or aortic ruptures. No statistical differences in overall mortality were noted between octogenarians and non-octogenarians at 30 days (7% vs 6%, p=NS), 12 months (18% vs 13%, p=NS) and 24 months (27% vs 15%, p=NS). However, at 5 years post-procedure, octogenarians had a significantly higher overall mortality than non-octogenarians (32% vs 17%, p=0.038). CONCLUSIONS: Advanced age is not a contraindication to thoracic endografting with favorable short and mid-term outcomes compared to non-octogenarians. |
| File Format | HTM / HTML |
| ISSN | 10107940 |
| e-ISSN | 1873734X |
| Journal | European Journal of Cardio-Thoracic Surgery |
| Issue Number | 3 |
| Volume Number | 34 |
| Language | English |
| Publisher | Oxford University Press |
| Publisher Date | 2008-09-01 |
| Publisher Place | Germany |
| Access Restriction | Open |
| Subject Keyword | Discipline Cardiology__semicolon__surgery Aorta, Thoracic Surgery Aortic Diseases Blood Vessel Prosthesis Implantation Minimally Invasive Surgical Procedures Aneurysm, Dissecting Aortic Aneurysm, Thoracic Blood Vessel Prosthesis Adverse Effects Epidemiologic Methods Stents Evaluation Studies |
| Content Type | Text |
| Resource Type | Article |
| Subject | Pulmonary and Respiratory Medicine Surgery Cardiology and Cardiovascular Medicine |
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