NDLI: YI 1.2 Ideal Cardiovascular Health Score Declines from Adolescence to Emerging Adulthood

Content Provider	Springer Nature : BioMed Central
Author	Park, Chloe Jones, Siana Williams, Suzanne Rapala, Alicja Taylor, Hannah Howe, Laura Fraser, Abigail Chaturvedi, Nish Hughes, Alun
Abstract	Purpose To define and compare cardiovascular (CV) health scores (CHS) from adolescence (17 yrs) to emerging adulthood (24 yrs) using longitudinal data from a large British birth cohort. Methods 3142 participants from the Avon Longitudinal Study of Parents and Children (ALSPAC) study attended clinical investigations at 17.8 ± 0.4 yrs and 24.0 ± 0.8 yrs (38% male). CV health was assessed using smoking status, body mass index (BMI), plasma glucose, cholesterol, sitting brachial blood pressure, left ventricle (LV) hypertrophy, arterial stiffness (carotid-to-femoral pulse wave velocity) and atherosclerosis (carotid intima-media thickness) metrics. Prevalence was stratified into poor (0_points), intermediate (1_point) and ideal (2_points) health categories and a composite, individual-level CHS for all 8 metrics was calculated (total range, 0–16 points). Prevalence of ideal health was assessed using ANOVA and linear mixed modelling assessed age##sex modifications. Results Overall CHS was high at 17 yrs but from 17–24 yrs the proportion of ideal scores decreased for all metrics, in both sexes (Table). The average overall CHS decreased from 14.97 ± 1.1 to 13.99 ± 1.4 in males (p < 0.0001) and 14.82 ± 1.2 to 14.28 ± 1.4 in females (p < 0.0001, age##sex p = 0.0001). Significant sex differences were observed in the proportion of individuals with ideal health at both ages, with males having a higher CHS than females at 17 yrs but a lower CHS at 24 yrs. Conclusions Despite being relatively early in the life-course, CV health declines from 17 yrs to 24 yrs in both sexes, and more substantially in males. Emerging adulthood is a distinct period of lifestyle change and an important time to control CV risk factors to improve future CV health. Male 0 1 Age 17 yrs 24 yrs Age0 Age1 Age2 Age3 Age4 Score 0 1 2 0 1 2 p 0 Score0 Score1 Score2 Score3 Score4 Smoking 22.6 19.3 58.1 27.8 35.6 36.6 <0.0001 27.8 Smoking0 Smoking1 Smoking2 Smoking3 Smoking4 BMI 4.9 13.3 82.1 10.4 30.0 59.6 <0.0001 6.7 BMI0 BMI1 BMI2 BMI3 BMI4 Glucose 0.4 9.1 90.5 0.6 34.7 64.7 <0.0001 0.3 Glucose0 Glucose1 Glucose2 Glucose3 Glucose4 Cholesterol 0.0 1.5 98.5 2.1 11.7 86.2 <0.0001 0.1 Cholesterol0 Cholesterol1 Cholesterol2 Cholesterol3 Cholesterol4 Blood pressure 0.2 0.5 99.3 0.6 5.4 94.0 <0.0002 0.3 Blood pressure0 Blood pressure1 Blood pressure2 Blood pressure3 Blood pressure4 LV hypertrophy 0.6 0.6 98.9 1.4 3.7 94.8 <0.0001 0.5 LV hypertrophy0 LV hypertrophy1 LV hypertrophy2 LV hypertrophy3 LV hypertrophy4 Arterial stiffness 0.5 0.9 98.6 4.8 6.7 88.5 <0.0001 0.0 Arterial stiffness0 Arterial stiffness1 Arterial stiffness2 Arterial stiffness3 Arterial stiffness4 Atherosclerosis 0.0 0.9 99.1 0.0 1.2 98.8 0.0005 0.0 Atherosclerosis0 Atherosclerosis1 Atherosclerosis2 Atherosclerosis3 Atherosclerosis4 Average CHS 14.97 ± 1.1 13.99 ± 1.4 <0.0001 14.82 ± 1.2 Average CHS0 Average CHS1 Average CHS2 Average CHS3 Average CHS4 Data are % of participants in each category for each risk factor. 0 = poor, 1 = intermediate and 2 = ideal. Age##sex p value for modification. Table
Related Links	https://arteryresearch.biomedcentral.com/counter/pdf/10.2991/artres.k.201209.002.pdf
Ending Page	S2
Page Count	1
Starting Page	S2
File Format	HTM / HTML
ISSN	18764401
DOI	10.2991/artres.k.201209.002
Journal	Artery Research
Issue Number	1
Volume Number	26
Language	English
Publisher	BioMed Central
Publisher Date	2020-12-31
Access Restriction	Open
Subject Keyword	Medicine Public Health Adolescents cardiovascular-aging birth-cohort sex-differences Medicine/Public Health
Content Type	Text
Resource Type	Synopsis
Subject	Physiology (medical) Physiology
Journal Impact Factor	0.9/2023
5-Year Journal Impact Factor	0.7/2023

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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