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| Content Provider | Springer Nature : BioMed Central |
|---|---|
| Author | Du, Yuan-Zhuo Liu, Jia-Hao Zheng, Fu-Chun Zhou, Qiang Guo, Ju |
| Abstract | Objectives The albumin–globulin ratio (AGR) is considered an important indicator reflecting an individual’s immune function and nutritional status, and it is closely associated with various health conditions. However, despite its widely studied correlations in numerous health fields, the link between AGR and Overactive Bladder (OAB) is still not completely comprehended. Methods Data were sourced from the National Health and Nutrition Examination Survey (NHANES) database, selecting adult samples spanning from 2007 to 2018. Through comprehensive questionnaires and laboratory tests, we gathered data pertinent to OAB and the AGR. To explore the association between AGR levels and the likelihood of developing OAB, we utilized advanced statistical techniques, such as weighted multivariate logistic regression and restricted cubic spline (RCS) models. Furthermore, we carried out subgroup analyses to assess the uniformity of this association across various demographics. Results After adjusting for relevant covariates, we discovered a marked negative correlation between AGR levels and the risk of OAB. As AGR increased, the incidence of OAB showed a declining trend (OR = 0.69; 95% CI 0.56–0.85). Furthermore, significant nonlinear dose–response relationship was observed between AGR levels and the risk of OAB (P < 0.001), and this association remained stable in stratified analyses. Conclusions Our results indicate that elevated AGR levels could be linked to a reduced risk of OAB. This observation highlights the potential role of AGR in assessing and preventing the occurrence of OAB. |
| Related Links | https://eurjmedres.biomedcentral.com/counter/pdf/10.1186/s40001-025-02441-6.pdf |
| Ending Page | 10 |
| Page Count | 10 |
| Starting Page | 1 |
| File Format | HTM / HTML |
| DOI | 10.1186/s40001-025-02441-6 |
| Journal | European Journal of Medical Research |
| Issue Number | 1 |
| Volume Number | 30 |
| Language | English |
| Publisher | BioMed Central |
| Publisher Date | 2025-04-02 |
| Access Restriction | Open |
| Subject Keyword | Medicine Public Health Infectious Diseases Internal Medicine Surgery Oncology Biomedicine Overactive bladder Albumin–globulin ratio NHANES Cross Sectional study Medicine/Public Health |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine |
| Journal Impact Factor | 2.8/2023 |
| 5-Year Journal Impact Factor | 2.9/2023 |
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