NDLI: Consumption of antibiotics in Brazil - an analysis of sales data between 2014 and 2019

Content Provider	Springer Nature : BioMed Central
Author	Lopes, Luciane Cruz Motter, Fabiane R. Carvalho-Soares, Mônica Da Luz
Abstract	Background Antibiotic consumption is a driver for the increase of antimicrobial resistance. The objective of this study is to analyze variations in antibiotic consumption and its appropriate use in Brazil from 2014 to 2019. Methods We conducted a time series study using the surveillance information system database (SNGPC) from the Brazilian Health Regulatory Agency. Antimicrobials sold in retail pharmacies were evaluated. All antimicrobials recorded for systemic use identified by the active ingredient were eligible. Compounded products and formulations for topic use (dermatological, gynecological, and eye/ear treatments) were excluded. The number of defined daily doses (DDDs)/1,000 inhabitants/day for each antibiotic was attributed. The number of DDDs per 1,000 inhabitants per day (DDIs) was used as a proxy for consumption. Results were stratified by regions and the average annual percentage change in the whole period studied was estimated. We used the WHO Access, Watch, and Reserve (AWaRe) framework to categorize antimicrobial drugs. Results An overall increase of 30% in consumption from 2014 to 2019 was observed in all Brazilian regions. Amoxicillin, azithromycin and cephalexin were the antimicrobials more consumed, with the Southeast region responsible for more than 50% of the antibiotic utilization. Among all antimicrobials analyzed 45.0% were classified as watch group in all Brazilian regions. Conclusion We observed a significant increase in antibiotics consumption from 2014 to 2019 in Brazil restricted to the Northeast and Central West regions. Almost half of the antibiotics consumed in Brazil were classified as watch group, highlighting the importance to promote rational use in this country.
Related Links	https://aricjournal.biomedcentral.com/counter/pdf/10.1186/s13756-024-01412-6.pdf
Ending Page	10
Page Count	10
Starting Page	1
File Format	HTM / HTML
ISSN	20472994
DOI	10.1186/s13756-024-01412-6
Journal	Antimicrobial Resistance & Infection Control
Issue Number	1
Volume Number	13
Language	English
Publisher	BioMed Central
Publisher Date	2024-06-09
Access Restriction	Open
Subject Keyword	Medical Microbiology Drug Resistance Infectious Diseases Antibiotic consumption Antimicrobial resistance Defined daily doses AWaRe Time-series study
Content Type	Text
Resource Type	Article
Subject	Public Health, Environmental and Occupational Health Infectious Diseases Microbiology (medical) Pharmacology (medical)
Journal Impact Factor	4.8/2023
5-Year Journal Impact Factor	5.8/2023

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Estimating antibiotics consumption in a tertiary care hospital in Islamabad using a WHO’s defined daily dose methodology

Association between quality of governance, antibiotic consumption, and antimicrobial resistance: an analysis of Italian regions

Antibiotic consumption and antimicrobial resistance in Poland; findings and implications

Antimicrobial consumption in five adult intensive care units: a 33-month surveillance study

WAAR (World Alliance against Antibiotic Resistance): Safeguarding antibiotics

Evaluation of Adult Outpatient Antibiotics Use at Jimma Medical Center (with Defined Daily Doses for Usage Metrics)

The 2017 global point prevalence survey of antimicrobial consumption and resistance in Canadian hospitals

Correction: Usefulness of dynamic regression time series models for studying the relationship between antimicrobial consumption and bacterial antimicrobial resistance in hospitals: a systematic review

Usefulness of dynamic regression time series models for studying the relationship between antimicrobial consumption and bacterial antimicrobial resistance in hospitals: a systematic review

Consumption of antibiotics in Brazil - an analysis of sales data between 2014 and 2019

Similar Documents

Estimating antibiotics consumption in a tertiary care hospital in Islamabad using a WHO’s defined daily dose methodology

Association between quality of governance, antibiotic consumption, and antimicrobial resistance: an analysis of Italian regions

Antibiotic consumption and antimicrobial resistance in Poland; findings and implications

Antimicrobial consumption in five adult intensive care units: a 33-month surveillance study

WAAR (World Alliance against Antibiotic Resistance): Safeguarding antibiotics

Evaluation of Adult Outpatient Antibiotics Use at Jimma Medical Center (with Defined Daily Doses for Usage Metrics)

The 2017 global point prevalence survey of antimicrobial consumption and resistance in Canadian hospitals

Correction: Usefulness of dynamic regression time series models for studying the relationship between antimicrobial consumption and bacterial antimicrobial resistance in hospitals: a systematic review

Usefulness of dynamic regression time series models for studying the relationship between antimicrobial consumption and bacterial antimicrobial resistance in hospitals: a systematic review

Consumption of antibiotics in Brazil - an analysis of sales data between 2014 and 2019