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| Content Provider | Springer Nature : BioMed Central |
|---|---|
| Author | Li, Li Hu, Na Li, Linzi Li, Liangyi |
| Abstract | Objective Percutaneous coronary intervention (PCI) can effectively restore myocardial perfusion in patients with ST-segment elevation myocardial infarction (STEMI). Nevertheless, STEMI patients may still experience a “no-reflow” phenomenon after PCI. Accordingly, this study focused on the clinical value of low-dose dobutamine stress myocardial contrast echocardiography (MCE) for evaluating myocardial microcirculation perfusion and long-term prognosis in STEMI patients after PCI. Methods This study included 70 STEMI patients receiving PCI. Low-dose dobutamine stress MCE was performed to detect viable myocardium at 72 h after PCI and quantitatively analyze myocardial microcirculation perfusion at 72 h and 6 months after PCI. Patients were categorized into dobutamine stress echocardiography (DSE)-positive and DSE-negative groups, followed by comparisons of LVEF. The 3-year survival of STEMI patients after PCI was analyzed. Results No adverse reactions occurred during low-dose dobutamine stress MCE. Low-dose dobutamine stress MCE effectively detected viable myocardium at 72 h after PCI (AUC: of 0.849). Under the basal or stress state, A, β, and A × β values of viable myocardium at 6 months after PCI were prominently higher than values at 72 h after PCI. A and A × β values of viable myocardium at 6 months after PCI were considerably higher in the stress state than in the basal state. LVEF and long-term survival rates after PCI were markedly higher in the DSE-positive group than in the DSE-negative group. Conclusion Low-dose dobutamine stress MCE is an effective evaluation method for myocardial perfusion, left ventricular function recovery, and poor long-term prognosis in STEMI patients after PCI. |
| Related Links | https://cardiothoracicsurgery.biomedcentral.com/counter/pdf/10.1186/s13019-024-03216-6.pdf |
| Ending Page | 9 |
| Page Count | 9 |
| Starting Page | 1 |
| File Format | HTM / HTML |
| ISSN | 17498090 |
| DOI | 10.1186/s13019-024-03216-6 |
| Journal | Journal of Cardiothoracic Surgery |
| Issue Number | 1 |
| Volume Number | 20 |
| Language | English |
| Publisher | BioMed Central |
| Publisher Date | 2025-02-13 |
| Access Restriction | Open |
| Subject Keyword | Cardiac Surgery Thoracic Surgery ST-segment elevation myocardial infarction Myocardial contrast echocardiography Dobutamine stress Percutaneous coronary intervention Myocardial perfusion Left ventricular function recovery Long-term prognosis |
| Content Type | Text |
| Resource Type | Article |
| Subject | Surgery Cardiology and Cardiovascular Medicine Pulmonary and Respiratory Medicine |
| Journal Impact Factor | 1.5/2023 |
| 5-Year Journal Impact Factor | 1.6/2023 |
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