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| Content Provider | Springer Nature : BioMed Central |
|---|---|
| Author | Ibrahim, Abubakar Khoo, Martina Irwan Ismail, Engku Husna Engku Hussain, Nik Hazlina Nik Zin, Anani Aila Mat Noordin, Liza Abdullah, Sarimah Mahdy, Zaleha Abdullah Lah, Nik Ahmad Zuky Nik |
| Abstract | Background This systematic review explores the level of oxidative stress (OS) markers during pregnancy and their correlation with complications. Unlike previous studies, it refrains from directly investigating the role of OS but instead synthesises data on the levels of these markers and their implications for various pregnancy-related complications such as preeclampsia, intrauterine growth restrictions, preterm premature rupture of membranes, preterm labour, gestational diabetes mellitus and miscarriages. Method Study Design Utilizing a systematic review approach, we conducted a comprehensive search across databases, including MEDLINE, CINAHL (EBSCOhost), ScienceDirect, Web of Science, and SCOPUS. Our search encompassed all publication years in English. Results After evaluating 54,173 records, 45 studies with a low risk of bias were selected for inclusion. This systematic review has underscored the importance of these markers in both physiological and pathological pregnancy states such as preeclampsia, intrauterine growth restrictions, preterm premature rupture of membranes, preterm labour, gestational diabetes mellitus and miscarriages. Conclusion This systematic review provides valuable insights into the role of OS in pregnancy and their connection to complications. These selected studies delved deeply into OS markers during pregnancy and their implications for associated complications. The comprehensive findings highlighted the significance of OS markers in both normal and pathological pregnancy conditions, paving the way for further research in this field. |
| Related Links | https://rbej.biomedcentral.com/counter/pdf/10.1186/s12958-024-01259-x.pdf |
| Ending Page | 12 |
| Page Count | 12 |
| Starting Page | 1 |
| File Format | HTM / HTML |
| ISSN | 14777827 |
| DOI | 10.1186/s12958-024-01259-x |
| Journal | Reproductive Biology and Endocrinology |
| Issue Number | 1 |
| Volume Number | 22 |
| Language | English |
| Publisher | BioMed Central |
| Publisher Date | 2024-08-02 |
| Access Restriction | Open |
| Subject Keyword | Reproductive Medicine Endocrinology Pregnancy Oxidative stress Biomarkers Antioxidants Pre-eclampsia Fetal growth restriction |
| Content Type | Text |
| Resource Type | Review |
| Subject | Endocrinology Obstetrics and Gynecology Developmental Biology Reproductive Medicine |
| Journal Impact Factor | 4.2/2023 |
| 5-Year Journal Impact Factor | 5.3/2023 |
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