NDLI: Impact of diabetes in patients waiting for invasive cardiac procedures during COVID-19 pandemic

Content Provider	Springer Nature : BioMed Central
Author	Moreno, Raúl Díez, José-Luis Diarte, José-Antonio Salinas, Pablo de la Torre Hernández, José María Andres-Cordón, Juan F. Trillo, Ramiro Briales, Juan Alonso Amat-Santos, Ignacio Romaguera, Rafael Díaz, José-Francisco Vaquerizo, Beatriz Ojeda, Soledad Cruz-González, Ignacio Morena-Salas, Daniel Pérez de Prado, Armando Sarnago, Fernando Portero, Pilar Gutierrez-Barrios, Alejandro Alfonso, Fernando Bosch, Eduard Pinar, Eduardo Ruiz-Arroyo, José-Ramón Ruiz-Quevedo, Valeriano Jiménez-Mazuecos, Jesús Lozano, Fernando Rumoroso, José-Ramón Novo, Enrique Irazusta, Francisco J. García del Blanco, Bruno Moreu, José Ballesteros-Pradas, Sara M. Frutos, Araceli Villa, Manuel Alegría-Barrero, Eduardo Lázaro, Rosa Paredes, Emilio
Abstract	Background During COVID-19 pandemic, elective invasive cardiac procedures (ICP) have been frequently cancelled or postponed. Consequences may be more evident in patients with diabetes. Objectives The objective was to identify the peculiarities of patients with DM among those in whom ICP were cancelled or postponed due to the COVID-19 pandemic, as well as to identify subgroups in which the influence of DM has higher impact on the clinical outcome. Methods We included 2,158 patients in whom an elective ICP was cancelled or postponed during COVID-19 pandemic in 37 hospitals in Spain. Among them, 700 (32.4%) were diabetics. Patients with and without diabetes were compared. Results Patients with diabetes were older and had a higher prevalence of other cardiovascular risk factors, previous cardiovascular history and co-morbidities. Diabetics had a higher mortality (3.0% vs. 1.0%; p = 0.001) and cardiovascular mortality (1.9% vs. 0.4%; p = 0.001). Differences were especially important in patients with valvular heart disease (mortality 6.9% vs 1.7% [p < 0.001] and cardiovascular mortality 4.9% vs 0.9% [p = 0.002] in patients with and without diabetes, respectively). In the multivariable analysis, diabetes remained as an independent risk factor both for overall and cardiovascular mortality. No significant interaction was found with other clinical variables. Conclusion Among patients in whom an elective invasive cardiac procedure is cancelled or postponed during COVID-19 pandemic, mortality and cardiovascular mortality is higher in patients with diabetes, irrespectively on other clinical conditions. These procedures should not be cancelled in patients with diabetes.
Related Links	https://cardiab.biomedcentral.com/counter/pdf/10.1186/s12933-021-01261-2.pdf
Ending Page	10
Page Count	10
Starting Page	1
File Format	HTM / HTML
ISSN	14752840
DOI	10.1186/s12933-021-01261-2
Journal	Cardiovascular Diabetology
Issue Number	1
Volume Number	20
Language	English
Publisher	BioMed Central
Publisher Date	2021-03-23
Access Restriction	Open
Subject Keyword	Diabetes Angiology Cardiology Interventional cardiology COVID-19 Mortality Waiting list
Content Type	Text
Resource Type	Article
Subject	Cardiology and Cardiovascular Medicine Internal Medicine Endocrinology, Diabetes and Metabolism
Journal Impact Factor	8.5/2023
5-Year Journal Impact Factor	8.9/2023

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
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