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| Content Provider | Springer Nature : BioMed Central |
|---|---|
| Author | Eraghi, Vida Zagradišnik, Lidija Medven Matasović, Mavro Vlahović, Dunja Huber, Doroteja Kurilj, Andrea Gudan Šoštarić-Zuckermann, Ivan-Conrado Artuković, Branka Buhin, Ivana Mihoković Ciprić, Iva Hohšteter, Marko |
| Abstract | Background Lymphoma is the most prevalent hematopoietic system tumor in dogs and holds significant clinical importance in veterinary medicine. However, the epidemiology of canine lymphoma in Croatia remains understudied. This retrospective study aims to describe the predominant lymphoma types in this population over 14 years and evaluate associations with sex, breed, and age. Results Among 28,681 canine cases referred to the Department of Veterinary Pathology, University of Zagreb, from 2009 to 2023, a total of 374 cases (1.30%) were diagnosed with lymphoma. Of these, 282 cases (75.40%) were purebred dogs, with the most affected breeds being Golden Retrievers (23, 6.15%), Labrador Retrievers (23, 6.15%), German Shepherds (14, 3.74%), and Boxers (14, 3.74%). Bullmastiffs (8.14%) had the highest number of lymphoma diagnoses among the referred breeds, followed by Airedale Terriers (6.67%) and German Shepherds (5.09%). The Maltese, though a popular breed, showed a low lymphoma rate of 0.40%, indicating no notable predisposition. Multicentric lymphoma (59, 53.64%) was the most common anatomical classification, followed by cutaneous (33, 30.00%) and alimentary lymphoma (13, 11.82%). The mean age at diagnosis was 8.27 ± 3.07 years, with most cases occurring between 5 and 10 years (207, 55.35%). Males (216, 57.75%) were more frequently affected than females (158, 42.24%), except among Golden Retrievers, where 69.56% of cases were female. Conclusion Our study reveals that the distribution of dogs with lymphomas, including type and anatomical classification, in terms of breed, sex and age, is consistent with existing literature, except in the cases of Golden Retrievers, Basset Hounds, and Scottish Terriers. Further molecular and environmental studies are recommended. |
| Related Links | https://bmcvetres.biomedcentral.com/counter/pdf/10.1186/s12917-025-04634-x.pdf |
| Ending Page | 7 |
| Page Count | 7 |
| Starting Page | 1 |
| File Format | HTM / HTML |
| ISSN | 17466148 |
| DOI | 10.1186/s12917-025-04634-x |
| Journal | BMC Veterinary Research |
| Issue Number | 1 |
| Volume Number | 21 |
| Language | English |
| Publisher | BioMed Central |
| Publisher Date | 2025-03-17 |
| Access Restriction | Open |
| Subject Keyword | Veterinary Medicine Veterinary Science Zoology Transgenics Canine lymphoma Croatia Retrospective study Cytology Immunohistochemistry Immunocytochemistry Veterinary Medicine/Veterinary Science |
| Content Type | Text |
| Resource Type | Article |
| Subject | Veterinary Medicine |
| Journal Impact Factor | 2.3/2023 |
| 5-Year Journal Impact Factor | 2.6/2023 |
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