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| Content Provider | Springer Nature : BioMed Central |
|---|---|
| Author | Colitti, Barbara Manassero, Luca Colombino, Elena Ferraris, Erica Ilaria Caccamo, Roberta Bertolotti, Luigi Bortolami, Alessio Bonfante, Francesco Papa, Valentina Cenacchi, Giovanna Calabrese, Fiorella Bozzetta, Elena Varello, Katia Capucchio, Maria Teresa Rosati, Sergio |
| Abstract | Background Interstitial lung disease is a heterogeneous group of conditions characterized by severe radiographic changes and clinicopathological findings. However, in the vast majority of cases, the cause remains unknown. Case description In the present study, we reported the clinical case of a 3 years old female Bull Terrier presented in October 2020 to the Advanced Diagnostic Imaging Department of the Turin Veterinary Teaching Hospital with a progressive pulmonary illness characterized by dyspnea, exercise intolerance, and a diffuse and severe pulmonary interstitial pattern at imaging investigations. Considering the clinical findings, the dog was included in a serological survey for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection in companion animals, showing positive results. Due to the further clinical worsening, the owners opted for euthanasia. At necroscopy, dog showed severe and chronic bronchopneumonia compatible with a Canine Idiopathic Pulmonary Fibrosis and with serological features linked to a SARS-CoV-2 infection. Conclusions The comparison of these lesions with those reported in humans affected by Coronavirus Disease 2019 (COVID-19) supports the hypothesis that these findings may be attributable to the post-acute sequelae of SARS-CoV-2 infection in a dog with breed predisposition to Canine Idiopathic Pulmonary Fibrosis (CIPF), although direct evidence of SARS-CoV-2 by molecular or antigenic approaches remained unsolved. |
| Related Links | https://bmcvetres.biomedcentral.com/counter/pdf/10.1186/s12917-022-03191-x.pdf |
| Ending Page | 8 |
| Page Count | 8 |
| Starting Page | 1 |
| File Format | HTM / HTML |
| ISSN | 17466148 |
| DOI | 10.1186/s12917-022-03191-x |
| Journal | BMC Veterinary Research |
| Issue Number | 1 |
| Volume Number | 18 |
| Language | English |
| Publisher | BioMed Central |
| Publisher Date | 2022-03-22 |
| Access Restriction | Open |
| Subject Keyword | Veterinary Medicine Veterinary Science Zoology Transgenics SARS-CoV-2 COVID-19 Dog Pneumonia Diagnosis Veterinary Medicine/Veterinary Science |
| Content Type | Text |
| Resource Type | Case study |
| Subject | Veterinary Medicine |
| Journal Impact Factor | 2.3/2023 |
| 5-Year Journal Impact Factor | 2.6/2023 |
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