NDLI: Analysis of uterine corporeal mesenchymal tumors occurring after menopause

Content Provider	Springer Nature : BioMed Central
Author	Ishidera, Yumi Yoshida, Hiroshi Oi, Yuka Katayama, Kayo Miyagi, Etsuko Hayashi, Hiroyuki Shigeta, Hiroyuki
Abstract	Objective Because it is difficult to diagnose accurately whether uterine corporeal mesenchymal tumors are benign or malignant before surgery, an understanding of the characteristics of patients with uterine sarcomas occurring in the postmenopausal period is required. Methods We retrospectively reviewed the cases of women who underwent surgery for uterine mesenchymal tumors at our hospital. Results Among 487 operated cases, 447 tumors occurred in the premenopausal period and 40 occurred in the postmenopausal period. Uterine sarcomas were observed in 5 cases (1.1%) during the premenopausal period and in 11 cases (28%) during the postmenopausal period. Among the postmenopausal patients, age, age at menopause, body mass index (BMI), tumor size, incidence of abnormal vaginal bleeding, serum tumor marker levels (cancer antigen 125, carbohydrate antigen 19–9, and carcinoembryonic antigen), and serum lactate dehydrogenase values were not significantly different between patients with benign tumors and those with malignant tumors. On the other hand, the incidence to have abnormal signal on MRI was significantly higher in patients with malignant tumors than in patients with benign tumors. Conclusion In our hospital, the incidence of malignant tumors in women with uterine corporeal mesenchymal tumors was much higher in postmenopausal patients than in premenopausal patients. Because it is generally not easy to diagnose uterine sarcomas before surgery, surgery should be positively considered when uterine sarcomas cannot be ruled out for patients in the postmenopausal period.
Related Links	https://bmcwomenshealth.biomedcentral.com/counter/pdf/10.1186/s12905-019-0714-5.pdf
Ending Page	6
Page Count	6
Starting Page	1
File Format	HTM / HTML
ISSN	14726874
DOI	10.1186/s12905-019-0714-5
Journal	BMC Women's Health
Issue Number	1
Volume Number	19
Language	English
Publisher	BioMed Central
Publisher Date	2019-01-18
Access Restriction	Open
Subject Keyword	Gynecology Maternal and Child Health Reproductive Medicine Leiomyoma uterine Leiomyosarcoma,uterine Postmenopausal period
Content Type	Text
Resource Type	Article
Subject	Obstetrics and Gynecology Reproductive Medicine
Journal Impact Factor	2.4/2023
5-Year Journal Impact Factor	2.9/2023

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