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| Content Provider | Springer Nature : BioMed Central |
|---|---|
| Author | de Castro, Ricardo Dias Mota, Ana Carolina Loureiro Gama de Oliveira Lima, Edeltrudes Batista, André Ulisses Dantas de Araújo Oliveira, Julyana Cavalcanti, Alessandro Leite |
| Abstract | Background Given the high prevalence of oral candidiasis and the restricted number of antifungal agents available to control infection, this study investigated the in vitro antifungal activity of alcohol vinegar on Candida spp. and its effect on the physical properties of acrylic resins. Methods Tests to determine the Minimum Inhibitory Concentration (MIC) and Minimum Fungicidal Concentration (MFC) of vinegar alcohol (0.04 g/ml of acetic acid) and nystatin (control) were performed. The antifungal activity of alcohol vinegar was assessed through microbial growth kinetic assays and inhibition of Candida albicans adhesion to acrylic resin at different intervals of time. Surface roughness and color of the acrylic resin were analyzed using a roughness meter and color analyzer device. Results Alcohol vinegar showed MIC75% and MFC62.5% of 2.5 mg/ml, with fungicidal effect from 120 min, differing from nystatin (p < 0.0001), which showed fungistatic effect. Alcohol vinegar caused greater inhibition of C. albicans adhesion to the acrylic resin (p ≤ 0.001) compared to nystatin and did not change the roughness and color parameters of the material. Conclusion Alcohol vinegar showed antifungal properties against Candida strains and caused no physical changes to the acrylic resin. |
| Related Links | https://bmcoralhealth.biomedcentral.com/counter/pdf/10.1186/s12903-015-0035-5.pdf |
| Ending Page | 7 |
| Page Count | 7 |
| Starting Page | 1 |
| File Format | HTM / HTML |
| ISSN | 14726831 |
| DOI | 10.1186/s12903-015-0035-5 |
| Journal | BMC Oral Health |
| Issue Number | 1 |
| Volume Number | 15 |
| Language | English |
| Publisher | BioMed Central |
| Publisher Date | 2015-04-28 |
| Access Restriction | Open |
| Subject Keyword | Dentistry Oral and Maxillofacial Surgery Candida albicans Candidiasis Oral Acetic acid Dental prosthesis |
| Content Type | Text |
| Resource Type | Article |
| Subject | Dentistry |
| Journal Impact Factor | 2.6/2023 |
| 5-Year Journal Impact Factor | 3.2/2023 |
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