NDLI: Gene expression profiles in Rana pirica tadpoles following exposure to a predation threat

Content Provider	Springer Nature : BioMed Central
Author	Mori, Tsukasa Yanagisawa, Yukio Kitani, Yoichiro Sugiyama, Manabu Kishida, Osamu Nishimura, Kinya
Abstract	Background Rana pirica tadpoles show morphological changes in response to a predation threat: larvae of the dragonfly Aeshna nigroflava induce heightened tail depth, whereas larval salamander Hynobius retardatus induce a bulgy morphology with heightened tail depth. Although both predators induce similar tail morphologies, it is possible that there are functional differences between these tail morphs. Results Here, we performed a discriminant microarray analysis using Xenopus laevis genome arrays to compare tail tissues of control and predator-exposed tadpoles. We identified 9 genes showing large-scale changes in their expression profile: ELAV-like1, methyltransferase like 7A, dolichyl-phosphate mannosyltransferase, laminin subunit beta-1, gremlin 1, BCL6 corepressor-like 1, and three genes of unknown identity. A further 80 genes showed greater than 5 fold differences in expression after exposure to dragonfly larvae and 81 genes showed altered expression after exposure to larval salamanders. Predation-threat responsive genes were identified by selecting genes that reverted to control levels of expression following removal of the predator. Thirteen genes were induced specifically by dragonfly larvae, nine others were salamander-specific, and sixteen were induced by both. Functional analyses indicated that some of the genes induced by dragonfly larvae caused an increase in laminins necessary for cell adhesion in the extracellular matrix. The higher expression of gremlin 1 and HIF1a genes after exposure to dragonfly larvae indicated an in vivo hypoxic reaction, while down-regulation of syndecan-2 may indicate impairment of angiogenesis. Exposure to larval salamanders caused down-regulation of XCIRP-1, which is known to inhibit expression of adhesion molecules; the tadpoles showed reduced expression of cα(E)-catenin, small muscle protein, dystrophin, and myosin light chain genes. Conclusion The connective tissue of tadpoles exposed to larval salamanders may be looser. The differences in gene expression profiles induced by the two predators suggest that there are functional differences between the altered tail tissues of the two groups of tadpoles.
Related Links	https://bmcgenomics.biomedcentral.com/counter/pdf/10.1186/s12864-015-1389-4.pdf
Ending Page	17
Page Count	17
Starting Page	1
File Format	HTM / HTML
ISSN	14712164
DOI	10.1186/s12864-015-1389-4
Journal	BMC Genomics
Issue Number	1
Volume Number	16
Language	English
Publisher	BioMed Central
Publisher Date	2015-04-02
Access Restriction	Open
Subject Keyword	Life Sciences Microarrays Proteomics Animal Genetics and Genomics Microbial Genetics and Genomics Plant Genetics and Genomics Cross-species microarray Tadpoles Discriminant analysis Predator-induced
Content Type	Text
Resource Type	Article
Subject	Biotechnology Genetics
Journal Impact Factor	3.5/2023
5-Year Journal Impact Factor	4.1/2023

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Gene expression profiles in Rana pirica tadpoles following exposure to a predation threat

Cross-species hybridisation of pig RNA to human nylon microarrays

Comparative gene expression between two yeast species

Comparison of gene expression microarray data with count-based RNA measurements informs microarray interpretation

Identification of biomarkers that distinguish chemical contaminants based on gene expression profiles

Variability of gene expression profiles in human blood and lymphoblastoid cell lines

Differential expression of skeletal muscle genes following administration of clenbuterol to exercised horses

Changes in the gene expression profiles of the brains of male European eels (Anguilla anguilla) during sexual maturation

Gene expression profiles in neurological tissues during West Nile virus infection: a critical meta-analysis

Gene expression profiles in Rana pirica tadpoles following exposure to a predation threat

Similar Documents

Gene expression profiles in Rana pirica tadpoles following exposure to a predation threat

Cross-species hybridisation of pig RNA to human nylon microarrays

Comparative gene expression between two yeast species

Comparison of gene expression microarray data with count-based RNA measurements informs microarray interpretation

Identification of biomarkers that distinguish chemical contaminants based on gene expression profiles

Variability of gene expression profiles in human blood and lymphoblastoid cell lines

Differential expression of skeletal muscle genes following administration of clenbuterol to exercised horses

Changes in the gene expression profiles of the brains of male European eels (Anguilla anguilla) during sexual maturation

Gene expression profiles in neurological tissues during West Nile virus infection: a critical meta-analysis

Gene expression profiles in Rana pirica tadpoles following exposure to a predation threat