NDLI: BIS and spectral entropy monitoring during sedation with midazolam/remifentanil and dexmedetomidine/remifentanil

Content Provider	Springer Nature : BioMed Central
Author	Absalom, Anthony R Menon, David K
Abstract	Haenggi and colleagues report considerable intra- and inter-individual variability in derived electroencephalogram (EEG) parameters (Bispectral Index (BIS), response entropy and state entropy) recorded in volunteers sedated with midazolam or dexmedetomidine infusions titrated to modified Ramsay scores of 2, 3 and 4, and a remifentanil infusion at a fixed target concentration. Possible explanations for the low, variable and fluctuating EEG parameters are that volunteers were intermittently asleep, and that remifentanil gave rise to a low amplitude, slowed EEG pattern despite maintained consciousness. BIS and entropy values should be interpreted in combination with clinical findings in patients sedated with these agents.
Related Links	https://ccforum.biomedcentral.com/counter/pdf/10.1186/cc7776.pdf
Ending Page	3
Page Count	3
Starting Page	1
File Format	HTM / HTML
ISSN	13648535
DOI	10.1186/cc7776
Journal	Critical Care
Issue Number	2
Volume Number	13
Language	English
Publisher	BioMed Central
Publisher Date	2009-04-28
Access Restriction	Open
Subject Keyword	Intensive Critical Care Medicine Emergency Medicine Remifentanil Dexmedetomidine State Entropy NREM Sleep Bispectral Index
Content Type	Text
Subject	Critical Care and Intensive Care Medicine
Journal Impact Factor	8.8/2023
5-Year Journal Impact Factor	10.4/2023

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BIS and spectral entropy monitoring during sedation with midazolam/remifentanil and dexmedetomidine/remifentanil